BACKGROUND Amyloidosis is a systemic disorder that results from the tissue deposition of various proteins with distinctive morphological characteristics. Conjunctival amyloidosis is a rare variant which is generally localized and not associated with systemic involvement. CASE REPORT We present here a case of 47-year-old female patient with right eyelid swelling that progressed over a 12 year ...

Amyloidosis is characterized by the systemic or localized extra cellular deposition of amyloid, a proteinaceous fibrillar material in various tissues and organs, mainly classified into primary (AL) or secondary (AA) groups according to the biochemical nature of the fibril forming protein. The histopathological diagnosis was made on Congo red stained biopsy specimens using polarized light and th...

Amyloidosis is a term applied to a diverse group of disorders that share the deposition of amyloid protein in various extracellular tissues. Systemic amyloidosis may involve almost any organ system in the body including regions in the head and neck; however, pharyngeal involvement is rare, with only 12 cases having been previously reported. Ten of these cases were localized disease, and only 2 ...

The amyloidoses are a group of protein-misfolding disorders characterized by the accumulation of amyloid fibrils formed from a variety of proteins. Currently, twentyeight different kinds of human and animal proteins, in intact or fragmented forms, have been found to be associated with pathological disorders such as Alzheimer’s disease, type II diabetes, prion diseases, dialysis-related amyloido...

Amyloidosis defines a pathological condition in which organ and tissue damage is related to the extracellular deposition of amyloid fibrils, deriving from specific proteins, the amyloid precursor proteins. More than 25 different precursor proteins are associated with different forms of amyloidosis, which are summarized in Tables 1 and 2. The modern nomenclature is based on the type of amyloid p...

Amyloidosis results from the deposition of amyloid proteins in organs and tissues. Clinically, it can be classified into systemic and localized forms. Here, we report a case of localized amyloidosis of the nasopharynx and neck. The initial presentation was a nasopharyngeal mass, and bilateral neck masses, mimicking nasopharyngeal carcinoma with neck metastasis. Computed tomographic scans of the...