primary or secondary hyperparathyroidism can present with a brown tumor of the mandible. involvement of other skull and facial bones is extremely rare. only a few cases with brown tumor of the orbital bones have been reported. an is year old girl with primary hyperparathyroidism presented with unilateral exophthalmos caused by brown tumor of the orbital roof, lite patient had a 1.5 cm palpable ...

CONTEXT Only limited information exists on the pathologic aspects of thyroid carcinomas with bone metastases, most large studies having concentrated mainly on their clinical features. OBJECTIVE To study in detail the morphologic features of thyroid carcinomas with skeletal metastases. DESIGN Seventy-nine cases of thyroid carcinoma with bone metastases treated at Memorial Sloan-Kettering Can...

HER-2 is an important prognostic factor in breast cancer, and its overexpression is observed in 20-60% of cases with micrometastases in the bone marrow. The aim of this study was to explore the potential functional role of HER-2 in primary breast tumors with bone metastases. Forty-eight primary breast tumors with simultaneous or non-simultaneous bone metastases were studied. The expression of h...

autologous bone is considered the first choice as material of cranioplasty because of its biological and anatomical features. however in some situations such as skull fractures or tumors the bone flap is not available or it must be replaced with a heterologous cranioplasty because of the development of surgical complications. authors of this study aimed to identify which are the best materials ...

Metastatic tumors of oral cavity are very rare, accounting for 1% of neoplasm in the area and their primary origin can be anywhere.[1] Most such patients were previously diagnosed with primary neoplasm. The literature states that in about 30% of cases of patients with gnathic bone metastases, the primary tumor is asymptomatic and not diagnosed.[2] The incidence of jaw bone metastasis is difficu...

In this study characteristics and distribution of primary bone and soft tissue tumors which were operated in Inonu University Turgut Ozal Medical Center Department of Orthopaedics and Traumatology between January 2000 and December 2016 and comparison with the literature is aimed. Our study is retrospective and descriptive and 710 patients [275 M, 435 F, mean age: 30,67 (1-92)] who hospitalized ...

BACKGROUND Tumors involving the hand skeleton are rare. However, a basic knowledge of hand tumors is necessary for every clinician. This is due to the importance of distinguishing typical benign tumors from life or limb threatening malignant ones. METHODS This study is a review of 99 cases of osseous hand tumors presented to the department of orthopedic surgery, Imam Khomeini Hospital in Tehr...

With integrated whole-body PET/MRI, a novel metabolic-anatomic imaging technique recently has been introduced into clinical practice. This review addresses PET/MRI of bone tumors, soft-tissue sarcoma, melanoma, and lymphoma. If PET/MRI literature is not yet available for some types of tumors, potential indications are based on available PET/CT and MRI data. PET/MRI seems to be of benefit in T-s...

BACKGROUND Bone is the most frequent site of systemic progression of breast cancer (BRC). Angiosuppressive therapy has now entered the management of progressing cancers, therefore it is clinically important to obtain information on vascular endothelial growth factor (VEGF) expression and microvessel density (MVD) of bone metastasis of BRC. MATERIALS AND METHODS VEGF expression and MVD were ev...

Objectives: FNAC plays a pivotal role in any lesion for the ease of diagnosing and treatment an ailment. The bone lesions has not been studied great vastness but it can definitely time taken on histopathology. aim study was to sensitivity, specificity, positive predictive value, negative value lesions, comparison cytological findings histopathological identify accuracy lesions. Methods: retrosp...