dissolution pressure and nozzle temperature effects on particle size and distribution were investigated for ress (rapid expansion of supercritical solution) process. supercritical co2 was used as solvent and ibuprofen was applied as the model component in all runs. the resulting ibuprofen nano-particles (about 50 nm in optimized runs) were analyzed by sem and laser diffraction particle size ana...

OBJECT Currently, mannitol is the recommended first choice for a hyperosmolar agent for use in patients with elevated intracranial pressure (ICP). Some authors have argued that hypertonic saline (HTS) might be a more effective agent; however, there is no consensus as to appropriate indications for use, the best concentration, and the best method of delivery. To answer these questions better, th...

BACKGROUND/AIM To evaluate efficacy and safety of bimatoprost 0.03% preservative-free (PF) ophthalmic solution versus bimatoprost 0.03% (Lumigan) ophthalmic solution for glaucoma or ocular hypertension. METHODS In this double-masked, parallel-group study, patients were randomised to bimatoprost PF or bimatoprost for 12 weeks. The primary analysis for non-inferiority was change from baseline i...

In this study, a novel method called “atmospheric pressure solution evaporation (APSE)” wasdeveloped for growing of Zinc Oxide (ZnO) nanostructures on Al2O3 surface. Zinc acetate dihydrate,Polyvinyl Pyrrolidone, and deionized water were used as precursor, capping, and solvent, respectively.The growth of ZnO nanostructures from evaporated solution was performed at three temperatures of300, 400, ...

In the present study, micellar-enhanced ultrafiltration (MEUF) was used to remove manganese (Mn) (II) from synthetic wastewater. The effects of different operational conditions on the filtration performance of MEUF or the membrane were studied. It was found that the transmembrane pressure has a major influence on the permeate flux and an insignificant effect on the rejection coefficient. The pe...

The aim of the present study is deriving an analytical solution to incompressible thermal flow in a micro-Couette geometry in the presence of a pressure gradient using Burnett equations with first- and second-order slip boundary conditions. The lower plate of the micro-Couette structure is stationary, whereas the upper plate moves at a constant velocity. Non-dimensional axial velocity and tempe...

Among the many force s to which hydraulic structures are exposed to, the forces induced by cavitation incident are of typical hydrodynamic unknown forces. The aim of this study is to define these forces as coupled fluid-structure interaction under two dynamic effects. The first dynamic effect which incorporates facilities for dealing with cavitation fluid is based on the appearance and bursting...