نتایج جستجو برای: pressure regulation
تعداد نتایج: 944149 فیلتر نتایج به سال:
The nucleus paragigantocellularis (PGI) is located in the rostral ventrolateral medulla and has noticeable connections with some other brain nuclei, such as locus ceruleus, nucleus raphe magnus and periaqueductal gray. In rats it is 3 mm in rostrocaudal and 1 mm in mediolateral and 1 mm in the dorsolateral aspect. Anatomically and functionally, PGI has been divided into two subnuclei, retrofaci...
MicroRNA-181a binds to the 3' untranslated region of messenger RNA (mRNA) for renin, a rate-limiting enzyme of the renin-angiotensin system. Our objective was to determine whether this molecular interaction translates into a clinically meaningful effect on blood pressure and whether circulating miR-181a is a measurable proxy of blood pressure. In 200 human kidneys from the TRANScriptome of rena...
The sympathetic nervous system plays an important role in the regulation of arterial pressure in normal man (Korner, 1979). Figure 1 shows a schema for how perturbation of arterial pressure in everyday arterial pressures well above the normal range, and are therefore deemed to be hypertensive. To what extent does failure of pressure regulation play a role in the development of hypertension, and...
Background and Aim: Hypertension is a chronic asymptomatic disease which is one of the most public health problems afflicting many of people over 35 years old in the world. The disease is the most important cause of all cardiovascular diseases, stroke, heart attack, renal disease, etc. It is also the primary contributor to disability and mortality, which is usually incurable but it must be mana...
AIM The Grainyhead-like 1 (GRHL1) transcription factor is tissue-specific and is very highly expressed in the kidney. In humans the GRHL1 gene is located at the chromosomal position 2p25. A locus conferring increased susceptibility to essential hypertension has been mapped to 2p25 in two independent studies, but the causative gene has never been identified. Furthermore, a statistically signific...
Gender has been reported to influence baroreflex heart rate regulation and baroreflex blood pressure buffering. We tested the hypothesis that gender influences baroreflex regulation of heart rate and sympathetic vasomotor tone. We recruited 32 normal-weight healthy subjects (17 men and 15 women). ECGs for heart rate, brachial and finger blood pressure, and muscle sympathetic nerve activity (MSN...
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