despite progress in pharmacological and surgical treatments of epilepsy, little is known about the processes that a healthy brain is rendered epileptic after seizure occurrence. growing evidence supports the involvement of inflammatory processes, both the adaptive immunity and systemic inflammatory response, in induction of individual seizures as well as in the epileptogenesis. clinical and exp...

background: very few studies have utilized specific criteria to assess mental disorders in brain tumor patients. this study aimed to diagnose mental disorders in this population using dsm-iv (depression, sleep, and mood) criteria. methods: from march 2007 to july 2009, the surgically treated patients with intracranial neoplasm were included in the study. these patients were examined in an ambul...

p2x7 receptors are purineric receptors that are extracellular atp-gated ion channel. these receptors require high dose or prolonged exposure to atp for initial activation. the activation of these receptors facilitates the formation of inflammasome which activates caspase 1. the p20 and p10 subunits of caspase 1 form active enzyme that then releases active interleukin (il)-1 β and il-18, tumor n...

hepatitis c can be cured and even eradicated by new “revolutionary” treatments. however, at present exorbitant prices, eastern european countries cannot afford the new treatments, while in western rich and developed countries (e.g. germany and france) they are already available. concerted efforts of governments, public health officials, and the community at large, are needed to negotiate agreem...

experiments were set up to estimate the effectiveness of clinoptilolite for the removal ofarsenate from aqueous solutions. the removal of arsenate by the exchanged forms was analyzed in thelight of the langmuir model of adsorption. a kinetic study of adsorption was carried out at differentintervals of time, and the kad values were calculated by using lagergren’s equation. adsorption ofarsenate ...

background trichoepithelioma is a rare benign skin lesion that originates from hair follicles. trichoepitheliomas are mostly seen in the scalp, nose, forehead, and upper lip. methods we present a large family of iranian origin with 15 individuals affected with multiple familial trichoepithelioma in four generations, and treated with three different methods. results trichoepithelioma is histolog...

conclusions significant improvement was noted at womac scale (pain level; 5 points, stiffness level; 2 points, physical function loss; 15 points, and total womac 22 points). osteoarthritis level of the patient was improved to grade i at radiological evaluation after a year. our case is the report that presents radiological evidence in addition to clinical findings of improvement of osteoarthrit...

background: antibiotics prescribed in the presumptuous treatment of infections may be ineffective if causative pathogens acquire resistance to prescribed antibiotics. in the absence of patient follow ups for treatment outcome assessments, healthcare providers may be unaware of the effectiveness of antibiotic treatments they provide. in the empiric treatment of infections particularly, such situ...

Forty-nine out of 60 persons who committed suicide had been under the care of 71 physicians within 6 months or less before committing suicide. Over two thirds of the patients had histories of suicide attempts or threats. These histories were known to only two fifths of the physicians responsible for their care, despite the information being readily available from other sources. There was substa...