Objective(s): Stroke may cause severe neuronal damage. The sesamin have been demonstrated to possess neuroprotection by its antioxidant and anti-inflammatory properties. One sesamin derivative was artificially composited, 1, 2-bis [(3-methoxyphenyl) methyl] ethane-1, 2-dicaroxylic acid (MMEDA) had been developed to study its antioxidative activity and neuroprotection. Materials and Methods: The...

The human placenta is crucial for prenatal development and good pregnancy outcome. Maternal diabetic disorder influences normal intrauterine of individual expresses itself in the placenta. Due to progress diagnostic methods metabolic compensation macroscopic signs associated with maternal diabetes, e.g., placentomegaly, occur nowadays rarely. In microscopic picture there are no structural diffe...

In newborns, hypoxia elicits defensive behaviors including awakening from sleep, body movements and crying. An inability to produce this defense response is a risk factor for sudden infant death syndrome and other respiratory control disorders. In this study, we examined the possibility that the defense response to hypoxia in newborns is partly determined by early exposure to hypoxia. We explor...

Macrophages accumulate in poorly vascularised and hypoxic sites including solid tumours, wounds and sites of infection and inflammation where they can be exposed to low levels of oxygen for long periods. Up to date, different studies have shown that a number of transcription factors are activated by hypoxia which in turn activate a broad array of mitogenic, pro-invasive, pro-angiogenic, and pro...

Introduction: Hypoxia is a common leading cause of detrimental effect on structure and function of tissue during increase in the production of reactive oxygen species that are generated during the re-oxygenation phase of intermittent continuous hypobaric hypoxia and contribute to physiological responses. This study was carried out to evaluate the effects of flaxseed (Fx) in reducing the inciden...

extract when a woman undergoes genetic testing of her fetus, the physiologic and emotional demands are great. careful nursing assessment and support are vital. the main benefit of prenatal genetic diagnosis is that women be given the opportunity to coping with your pregnancy where fetal abnormalities has been diagnosed or achieve  to a complete relaxation with  the positive results obtained . e...