introduction: the purpose of this study was to compare the efficacy and side effects of two different misoprostol regimens for second-trimester pregnancy termination. methods: 60 consenting women who were at 14 to 28 weeks of gestation with indications for pregnancy termination were randomly assigned to two equal groups to receive either vaginal or oral misoprostol. the dosing regimen was 400µg...

Background: Induced abortion is the medical or surgical termination of pregnancy before fetal viability. It has maternal or fetal indications. The aim of the present study was to evaluate the efficacy of the combination of methotrexate and misoprostol for termination of the pregnancy in the first trimester. Methods: This analytic study was performed on 100 women at the first trimester of pregna...

Acute liver failure (ALF) during pregnancy is very uncommon. Pregnancy-specific liver conditions like hemolysis, elevated liver enzymes, and low platelets (HELLP) syndrome and acute fatty liver of pregnancy can cause ALF at term or postpartum, but, typically occur during the third trimester. Most of these patients recover spontaneously after delivery, but, on occasion, they require liver transp...

OBJECTIVE To determine the main dietary patterns of pregnant women during each of the three trimesters of pregnancy and to examine associated nutrient intakes. DESIGN Participants completed a 3 d food diary during each trimester of pregnancy. Thirty-six food groups were created and dietary patterns were derived using k-means cluster analysis. SETTING National Maternity Hospital, Dublin, Ire...

background: a significant number of pregnancies, particularly in women with previous histories of infertility, are associated with fetal abnormalities. methods such as the nuchal translucency (nt) measurement enable us to identify more pregnancies with chromosomal abnormalities. materials and methods: this analytic cross-sectional study was performed in 446 pregnant women at 11-14 weeks gestati...

Background: High maternal hemoglobin (Hb) concentration was considered a risk factor for the developing of pregnancy hypertension. The purpose of this study was to determine whether high maternal Hb concentration in first trimesters associated with pregnancy induced hypertension in Iranian nulliparous women. Methods: This study was carried out in teaching hospital in Sari, Iran. Samples were ob...

BACKGROUND Evidence suggests that the hormonal milieu of pregnancy is an important determinant of subsequent cancer and other chronic diseases in both the mother and the offspring. Many of the existing maternity and birth cohorts include specimens drawn only once during pregnancy. How well a single blood specimen collected during a pregnancy characterizes exposure to these hormones throughout g...

BACKGROUND Thyroid dysfunction during pregnancy is associated with multiple adverse outcomes, but whether all women should be screened for thyroid disorders during pregnancy remains controversial. OBJECTIVE To evaluate the effectiveness of the targeted high risk case-finding approach for identifying women with thyroid dysfunction during the first and second trimesters of pregnancy. METHODS ...

BACKGROUND The objective of this study was to evaluate the clinical outcomes and to discuss the management of women presenting with an invasive cervical cancer during pregnancy. PATIENTS AND METHODS We retrospectively reviewed patients treated for an invasive cervical cancer diagnosed during pregnancy between 1985 and 2000 in our institution. RESULTS Twenty-one pregnant patients among a tot...