prefoldin

Putative biological predictors of treatment response in bipolar disorders

2017

Suzanne D. Gonzalez Aislinn J. Williams Caren J. Blacker Jennifer L. Vande Voort Kathryn M. Schak Charles B. Nemeroff Alik S. Widge Mauricio Tohen

http://dx.doi.org/10.1016/j.pmip.2016.11.003 2468-1717/ 2016 Elsevier Inc. All rights reserved. Abbreviations: BD, bipolar disorder; CSF, cerebrospinal fluid; BDNF, brain-derived neurotrophic factor; NT3, neurotrophin-3; NT4, neurotrophin-4; NGF, nerve factor; Trk, tyrosine kinase receptor; p75, TNF receptor superfamily member 1B; CNS, central nervous system; MDD, major depressive disorder; DLP...

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Eukaryotic Chaperonins: Lubricating the Folding of WD-repeat Proteins

Journal: :Current Biology 2003

Elizabeth A. Craig

For most proteins of the eukaryotic cytosol, the folding pathways are still largely a mystery, even though many cytosolic chaperones have been identified, including multiple members of the heat shock protein (Hsp) 70 family, Hsp90 and the chaperonin, CCT/TRiC. Particularly puzzling has been the role of CCT, a distant cousin of the prokaryotic chaperonin GroEL, found in eukaryotes and archea. Gr...

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Eukaryotic Chaperonins: Lubricating the Folding of WD-repeat Proteins Dispatch

2003

Elizabeth A. Craig

For most proteins of the eukaryotic cytosol, the folding pathways are still largely a mystery, even though many cytosolic chaperones have been identified, including multiple members of the heat shock protein (Hsp) 70 family, Hsp90 and the chaperonin, CCT/TRiC. Particularly puzzling has been the role of CCT, a distant cousin of the prokaryotic chaperonin GroEL, found in eukaryotes and archea. Gr...

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