Maternal serum uric acid was determined in 30 preeclamptic and 20 normal pregnant females in their third trimester. Serum uric acid was 3.52± 0.75 in normal pregnancies and 6.03 ± 1.67 in preeclamptic pregnancies. This increase in serum uric acid was highly significant (P<0.001). There was no influence of parity and maternal age on serum uric acid. Serum uric acid levels increased significantly...

BACKGROUND: Preeclampsia is hypertension in pregnancy which are characterized by high blood pressure, proteinuria that occur after 20 weeks of GA. remains a massive cause maternal morbidity and mortality 50.000 death annually. The preeclampsia still unclear but there possibility caused immunological processes micro placenta environment during the early age pregnancy. It suggested cytokines such...

The purpose of this study was to measure the level of anticardiolipin antibodies in preeclamptic pregnant women to verify a possible association between the presence of these antibodies and the development of the syndrome. A total of 36 pregnant women with preeclampsia and 19 women with normal pregnancy were evaluated. Anticardiolipin antibodies were determined by enzyme immunoassay. The reacti...

OBJECTIVE To investigate the possible correlation between plasma malondialdehyde and homocysteine levels of preeclamptic patients. DESIGN Venous blood samples of 20 preeclamptics and 20 healthy pregnant controls were collected. Plasma malondialdehyde and homocysteine concentrations were measured and the correlation between them was investigated. Mann Whitney U test and Spearman correlation an...

background and objective: the aim of this study was to determine the level of plasma high sensitive c-reactive protein (hs-crp) in preeclampsia and to compare hs-crp levels between normal pregnant women, mild preeclamptic, and severe preeclamptic women. materials and methods: serum hs-crp levels were investigated in 40 cases of normal pregnant women, 37 cases with mild preeclampsia and 38 cases...

background :   a  lot  of  studies  have  shown  periodontal  diseases  as  a  risk  factor  for  adverse  pregnancy  out­comes. the  as­sociation  between  periodontitis  and  preeclampsia  has  been  studied  recently  with  contro­versy. considering  the  importance  of  preventing  preeclampsia  as  a  dangerous  and  life-threatening  disease  in  pregnant  women,  the  pre­sent  study  wa...

background: previous studies have shown that preeclampsia is associated with elevated maternal serum homocysteine levels, but few studies have evaluated homocysteine levels in amniotic fluid in these patients. the purpose of this study was to compare amniotic fluid homocysteine levels in preeclamptic women, with those of normal pregnant women. methods: a cross sectional study was done on 46 pre...

Preeclampsia is associated with structural/functional alterations in placental and maternal vasculature. Voltage-dependant potassium channels encoded by KCNQ1-5 genes have been detected in several types of blood vessels where they promote vascular relaxation. Voltage-dependant potassium channel function can be modulated by KCNE1-5-encoded accessory proteins. The aim of this study was to determi...

The activity of ADAMTS13, the von Willebrand factor (VWF) cleaving protease is low in several conditions, including HELLP (haemolysis, elevated liver enzymes, and low platelet count) syndrome. As HELLP syndrome develops in most cases on the basis of preeclampsia, our aim was to determine whether plasma ADAMTS13 activity is decreased in preeclampsia. Sixty-seven preeclamptic patients, 70 healthy...

background: severe preeclampsia is a quite well-known entity with high incidence of both maternal and fetal morbidity and mortality. although little is known about its etiology, inherited disorders of hemostasis and antiphospholipid syndrome have been postulated as common causes. the present study was conducted to evaluate the association of these two entities with preeclampsia in a group of ir...