نتایج جستجو برای: pr

تعداد نتایج: 31161  

Journal: :Revista de saude publica 2012
Clóvis Arlindo de Sousa Chester Luiz Galvão César Marilisa Berti de Azevedo Barros Luana Carandina Moisés Goldbaum Júlio Cesar Rodrigues Pereira

OBJECTIVE To assess the prevalence of acute bronchitis, rhinitis, and sinusitis among children and adolescents and identify associated factors. METHODS This is a population-based, cross-sectional study. A household survey was conducted with 1,185 children and adolescents from the city of São Paulo (Southeastern Brazil), from 2008 to 2009. The participants were selected by means of probability...

Journal: :The Journal of clinical endocrinology and metabolism 2002
Sam Mesiano Eng-Cheng Chan John T Fitter Kenneth Kwek George Yeo Roger Smith

In human parturition, progesterone withdrawal and estrogen activation are not mediated by changes in progesterone and estrogen levels. Instead, these events could be facilitated by changes in the responsiveness of the myometrium to progesterone and estrogens via changes in PR and ER expression. We hypothesized that functional progesterone withdrawal occurs by increased expression of the type A ...

Journal: :Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 2013
Kee Chan Mai Ngan Lai Erik J Groessl Amresh D Hanchate John B Wong Jack A Clark Steven M Asch Allen L Gifford Samuel B Ho

BACKGROUND & AIMS The Veterans Health Administration (VHA) is the largest single provider of care for hepatitis C virus (HCV) infection in the United States. We analyzed the cost effectiveness of treatment with the HCV protease inhibitors boceprevir and telaprevir in a defined managed care population of 102,851 patients with untreated chronic genotype 1 infection. METHODS We used a decision-a...

Journal: :Antimicrobial agents and chemotherapy 1989
G C Palmer M J Ordy R D Simmons J C Strand L A Radov G B Mullen C R Kinsolving V St Georgiev J T Mitchell S D Allen

Routine in vitro screening of a new synthetic series of 3,5-substituted 2-methylisoxazolidines revealed that three imidazole analogs (PR 967-248, PR 967-234, and PR 969-566) and, to a lesser extent, a triazole analog (PR 988-399) exerted rather potent antifungal activity against three systemic and four dermatophytic classes of fungi. When tested in vivo for ability to eradicate Candida vaginiti...

ژورنال: :پژوهش فیزیک ایران 0
شعبان رضا قربانی sr ghorbani ferdowsi university of mashhadدانشگاه فردوسی مشهد ربابه یزدی زاده r yazdizadeh hakim sabzevari universityدانشگاه حکیم سبزواری

ترکیبات بس بلور ابررسانای nd1-xprxba2cu3o7- δ در بازه آلایش( 0.3 ≥ x ≥ 0 ) به روش استاندارد پودر حالت جامد ساخته شده اند. خواص ترابردی و ابررسانایی آنها با اندازه گیری مقاومت ویژه الکتریکی و توان گرماالکتریسیته به صورت تابعی از دما و غلظت آلایش مطالعه شده است. با افزایش غلظت آلایش مقاومت الکتریکی و توان گرماالکتریسیته در دمای اتاق افزایش می یابند. دمای شبه گاف به صورت تابعی از چگالی آلایش، از ر...

1998
Tao Wu Christian Schlegel

The performance of the adaptive projection receiver (PR), a recently proposed joint detector for CDMA with error control coding, is investigated. It is shown that the adaptive version of the PR performs better than the algebraic PR. A close approximation of the error probability for the adaptive PR is derived. The performance improvement of the adaptive PR, which is of the order of 1-2dB in Eb=...

2016
Jia-Yuan Sun San-Gang Wu Feng-Yan Li Huan-Xin Lin Zhen-Yu He

BACKGROUND To assess the prognostic value of progesterone receptor (PR) expression in patients with hormone receptor-positive and human epidermal growth factor receptor 2 (HER2)-negative breast cancer subgroups. METHODS A retrospective review of breast cancer patients who underwent mastectomy or breast-conserving surgery between January 1998 and December 2007 was performed. The prognostic imp...

2015
Young Hsu Young C. Hsu Marc J. Tetel

The ovarian steroid hormones estradiol (E) and progesterone (P) play important roles in reproductive physiology and behavior. The effects of E and P are mediated by their respective receptors, estrogen receptor (ER) and progestin receptor (PR) which function as transcription factors. PR is expressed as two isoforms, full length PR-B and the N-terminally truncated PR-A, by the induction of E in ...

2015
Kalpana D. Acharya Sarah D. Finkelstein Elizabeth P. Bless Sabin A. Nettles Biserka Mulac-Jericevic Orla M. Conneely Shaila K. Mani Marc J. Tetel

Estrogens act in brain to profoundly influence neurogenesis, sexual differentiation, neuroprotection, cognition, energy homeostasis, and female reproductive behavior and physiology through a variety of mechanisms, including the induction of progestin receptors (PRs). PRs are expressed as two isoforms, PR-A and PR-B, that have distinct functions in physiology and behavior. Because these PR isofo...

Journal: :Molecular endocrinology 2007
Viroj Boonyaratanakornkit Eileen McGowan Lori Sherman Michael A Mancini Boris J Cheskis Dean P Edwards

Human progesterone receptor (PR) contains a motif that interacts with the SH3 domain of Src and mediates rapid activation of Src and downstream MAPK (Erk-1/-2) without relying on the transcriptional activity of the receptor. Here we investigated the role and intracellular location of this nontranscriptional activity of PR. Progestin activation of Src/MAPK occurred outside the nucleus with the B...

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