Magnesium assays are being increasingly requested in hospitals and clinical research institutions. The ionized form of magnesium (iMg) is regarded as the biologically active fraction. Ionophore-based potentiometric sensors can determine iMg and apply a selectivity correction for co-existing interfering electrolytes, e.g. Ca 2+ . This technology has been used in several commercial blood analyzer...

The pH-sensitive chromoionophores brought the dream of the ion-selective membrane scientist close to realization. With the help of these molecules, one can build pH-sensitive, ion-selective electrodes and look into the bulk of solvent polymeric membranes during potentiometric measurements (spectropotentiometry) and image concentration profiles in situ with high spatial and temporal resolution. ...