Cadmium is a hazardous heavy metal existing ubiquitously in the environment, but the mechanism of cadmium transport into mammalian cells has been poorly understood. Recently, we have established a cadmium-resistant cell line (Cd-rB5) from immortalized metallothionein-null mouse cells, and found that Cd-rB5 cells exhibited a marked decrease in cadmium uptake. To investigate the mechanism of alte...

Effect of selenium on uptake of cadmium in the benthic marine invertebrates Asterias rubens, Mytilus edulis, Littorina littorea, and Arenicola marina was investigated in a series of laboratory experiments. A. rubens exposed to 200 ~cg Cd 1-' alone took up cadmium in body wall, pyloric caeca, and tube feet at initial rates of 1 to 2 pg Cd g-' dry wt d-'; steady state concentrations of 10 to 30 p...

If a sartorius muscle of frog is pretreated for 30 min. with a hyposmotic Ringer's (called "hyposmotic potassium chloride") in which all sodium chloride is replaced by 23 mM potassium chloride, and then is immersed in normal Ringer's for about 40 min., a twitch of normal size can be elicited although the potassium contracture is almost completely abolished. During the time that this selective i...

background: treatment of cesarean scar pregnancy (csp) is controversial. the objective of this study was to report our successful experience in the medical treatment of csp with potassium chloride (kcl) and methotrexate. case: this is a case series of six patients between 6-12 gestational weeks with the diagnosis of csp.  in five cases the fetus was alive and in one case, despite being at a ges...

background: there has been increasing awareness throughout the world regarding the remarkable decrease in amphibian population. for such amphibian population decline several causes have been given. cadmium, a heavy metal is released both from natural sources (leaching of cadmium rich soils) and anthropogenic activities to the aquatic and terrestrial environments. this study evaluated the toxici...

This study was designed to evaluate the effects of simultaneous coexposure to inorganic mercury and cadmium on the renal and hepatic disposition of each metal. Dispositional changes were assessed in rats 1 h and 24 h after the coexposure to relatively low doses of the metals (which individually are nonnephrotoxic in rats). The rational for studying mercury and cadmium is that both of these meta...

The intracellular concentrations of sodium, chloride, phosphorus and potassium under normal conditions in pavement epithelial (PE) cells of brown trout (Salmo trutta) gill were 66, 51, 87 and 88 mmol l-1 respectively. The concentrations of these elements under identical conditions in mitochondria-rich (MR) cells were not significantly different, except for that of chlorine, which was lower in M...