an efficient and environmentally friendly procedure for one-pot synthesis of 13-acetyl-9-methyl-11-ox-8-oxa-10,12-diazatricyclo [7.3.1. ] trideca-2,4,6-triene from salicylaldehyde, acetylaceton and urea via biginelli condensation and intramolecular michael-addition by using magnesium bromide as an expensive and easily available catalyst under solvent-free condition is desired. the structural el...

A simple and environmentally benign procedure for the synthesis of 14-aryl-14H-dibenzo[a,j]xanthenes by a one-pot condensation of 2-naphthol with aromatic aldehyde in the presence of [Et3NH][HSO4] as an acidic ionic liquid catalyst under solvent-free conditions has been developed. The reaction work-up is very simple and the catalyst can be easily separated from the reaction mixture and reused s...

Iso-butyric acid as a new, simple, and expensive solvent/catalyst was successfully used for the chemoselective Fischer’s synthesis of indolenines derivatives 3a-r by one-pot condensation reaction of various phenylhydrazines 1a-e with the substituted acetophenones 2a-c at reflux conditions. In this protocol, all products 3a-r were obtained in high yields and short reaction time. The structures o...

Alkali and alkaline earth metals hydrogen sulfate catalyzed the one-pot three component condensation reactions of aldehydes, 1,3-dicarbonyl compounds and urea or thiourea under solvent-free conditions leading to 3,4-dihydropyrimidin-2(1H)-ones in high yields at 80 °C. Our results showed that Biginelli reaction not only is pH dependent, but the cation of catalyst plays an importan...

This paper describes the applicability of 1,3-dichloro-5,5-dimethylhydantoin, as a cheap, stable and commercially available catalyst, in the promotion of the synthesis of 1,8-dioxo-octahydro-xanthenes (DOXOs) via the one-pot condensation of aldehydes and cyclic 1,3-dicarbonyl compounds. This novel synthetic method has the advantages of high yields, short reaction times, low cost and av...

A simple and environmentally benign procedure for the synthesis of 14-aryl-14H-dibenzo[a,j]xanthenes by a one-pot condensation of 2-naphthol with aromatic aldehyde in the presence of [Et3NH][HSO4] as an acidic ionic liquid catalyst under solvent-free conditions has been developed. The reaction work-up is very simple and the catalyst can be easily separated from the reaction mixture and reused s...

     A very efficient one-pot three-component synthesis of pyran derivatives has been improved by condensation of aldehydes and malononitrile with dimedone under 80 °C using sucrose as natural and biodegradable catalyst in water. This method offers some advantages including inexpensive, high to quantitative yields, short reaction time, and easy work-up. Therefore, this methodology is entirely g...

A practical and green approach for the one-pot multicomponent synthesis of fused tetrazolo[1,5-a]quinazoline derivatives has been described via the condensation of 5- aminotetrazole, dimedone, and various aldehydes using 1-butyl-3-methylimidazolium tetrachloroaluminate [bmim]Cl/AlCl3, as a catalyst and task-specific ionic liquid medium. The catalyst was showed remarkable advantages in compariso...

An improved, simple, and facile synthesis of 3,4-dihydropyrimidin-2(1H)-ones by employing three-component, one-pot condensation reaction of β-keto ester, aromatic aldehydes, and urea or N-methylurea using LaCl3/ClCH2COOH as an inexpensive and green chemistry catalyst system under solvent-free conditions described. Compared with the classicalBiginelli reaction conditions, this method has the adv...

a simple and environmentally benign procedure for the synthesis of 14-aryl-14h-dibenzo[a,j]xanthenes by a one-pot condensation of 2-naphthol with aromatic aldehyde in the presence of [et3nh][hso4] as an acidic ionic liquid catalyst under solvent-free conditions has been developed. the reaction work-up is very simple and the catalyst can be easily separated from the reaction mixture and reused s...