OBJECTIVES To investigate the association between use of typical and atypical antipsychotic drugs and incidence of stroke in patients with and without dementia. DESIGN Self controlled case series. SETTING UK based electronic primary care records in the general practice research database (GPRD). PARTICIPANTS All patients registered in the database with a recorded incident stroke and at lea...

Background and Purpose—Stroke and dementia are major health problems in the elderly. We examined the prevalence and incidence of stroke and their relation to dementia in a representative sample of 494 subjects 85 years of age from Gothenburg, Sweden, who were followed up to 88 years of age. Methods—Information on stroke was obtained from an inpatient hospital linkage system, death certificates,...

The use of the cognitive test battery Nordic Stroke Driver Screening Assessment (NorSDSA) has increased, sometimes as a stand-alone test to evaluate fitness to drive, also for non-stroke patients such as patients suffering from cognitive deficits/dementia, approaches that may be questioned. The objective of the study was to determine whether the NorSDSA could predict an on-road test result, for...

BACKGROUND Dementia is common in end-stage renal disease (ESRD) patients on hemodialysis (HD) and is associated with worse outcomes. This study aimed to investigate the risk of major adverse cardiac and cerebrovascular event (MACCE) in elderly patients with dementia initiating HD. METHODS Using the database from the Health Insurance Review & Assessment Service, we analyzed 10,171 patients age...

BACKGROUND Stroke is a common cause of physical disability but is also strongly associated with cognitive impairment and a risk for future dementia. Despite national clinical guidelines, the service provided for stroke survivors with cognitive and memory difficulties varies across localities. This study critically evaluated the views of healthcare professionals about barriers and facilitators t...

Evidence suggests that education protects from dementia by enhancing cognitive reserve. However, this may be influenced by several socio-demographic factors. Rising numbers of dementia in India, high levels of illiteracy and heterogeneity in socio-demographic factors provide an opportunity to explore this relationship. Objective To study the association between education and age at dementia o...

BACKGROUND AND PURPOSE The American Heart Association developed the ideal cardiovascular health (CVH) index as a simple tool to promote CVH; yet, its association with brain atrophy and dementia remains unexamined. METHODS Our aim was to investigate the prospective association of ideal CVH with vascular brain injury, including the 10-year risks of incident stroke and dementia, as well as cogni...

BACKGROUND AND PURPOSE Stroke and dementia are major health problems in the elderly. We examined the prevalence and incidence of stroke and their relation to dementia in a representative sample of 494 subjects 85 years of age from Gothenburg, Sweden, who were followed up to 88 years of age. METHODS Information on stroke was obtained from an inpatient hospital linkage system, death certificate...