The signaling mechanisms for glycosylphosphatidylinositol-anchored receptors (GPI-ARs) have been investigated by tracking single molecules in living cells. Upon the engagement or colloidal gold-induced cross-linking of CD59 (and other GPI-ARs) at physiological levels, CD59 clusters containing three to nine CD59 molecules were formed, and single molecules of Galphai2 or Lyn (GFP conjugates) exhi...

Dynamic stall is an aerodynamic phenomenon encountered when rotorcraft operate near performance boundaries typical of high-speed or maneuvering flight. The complex, highly non-linear aerodynamics and associated interaction with the structures induce exceptionally high loads, violent vibrations, reduced handling qualities, and a reduction in fatigue life. The prediction of dynamic stall remains ...

Without additional support policies, clean cooking could become unaffordable for about 470 million people by 2030 if a post-pandemic recovery is slow, and 200 under ambitious climate mitigation action. Acceleration of transitions tapping into pandemic funds to target the poorest regions globally urgently needed.

Mycoplasma mobile is a bacterium that uses a unique mechanism to glide on solid surfaces at a velocity of up to 4.5 μm/s. Its gliding machinery comprises hundreds of units that generate the force for gliding based on the energy derived from ATP; the units catch and pull sialylated oligosaccharides fixed to solid surfaces. In this study, we measured the stall force of wild-type and mutant strain...

Although cache-coherent shared-memory multiprocessors are sometimes used to run commercial workloads, little work has been done to characterize how well they support these work-loads. In particular, we do not have many insights on the demands of commercial workloads on the memory subsystem of such machines. These issues are important because of the large market for commercial applications. In t...

Covert-feathers-inspired passive flow control is beneficial for aerodynamic performance at post-stall angles of attack. However, most studies model covert feathers as a rigidly attached or freely moving flap on wing. The mounted via torsional spring, emblematic to the finite stiffness bird feathers, has remained unexplored. We simulate strongly coupled fluid-structure interactions past stationa...

Parallel compressor theory (PCT) is commonly used to estimate effects of inlet distortion on performance. As well as compressor, the actual inflow pump also nonuniform and unfavorable for performances. Nowadays, insufficient understanding performance restricts its development. Therefore, this paper applies PCT predict external characteristics evaluate internal flow instability waterjet under in...

Title of Dissertation: A Coupled CFD/CSD Investigation of the Effects of Leading Edge Slat on Rotor Performance Asitav Mishra, Doctor of Philosophy, 2012 Dissertation directed by: Associate Professor James D. Baeder Department of Aerospace Engineering A coupled Computational Fluid Dynamic (CFD) and Computational Structural Dynamics (CSD) methodology is extended to analyze the effectiveness of a...

We use data from the Demographic and Health Surveys to examine the patterns of stall in fertility decline in four Eastern African countries. Contrary to patterns of fertility transition in Africa that cut across various socio-economic and geographical groups within countries, we find strong selectivity of fertility stall across different groups and regions in all four countries. In both Kenya a...

The alula is a small structure located at the joint between the hand-wing and arm-wing of birds and is known to be used in slow flight with high angles of attack such as landing. It is assumed to function similarly to a leading-edge slat that increases lift and delays stall. However, in spite of its universal presence in flying birds and the wide acceptance of stall delay as its main function, ...