The Spitz nevus was first described as the “melanoma of childhood” or “juvenile melanoma” by Sophie Spitz in 1948 (1). Most spitzoid melanocytic proliferations can be classified as benign Spitz nevi or spitzoid melanomas based on published criteria (2-3). However, a subset of spitzoid lesions have histological features that deviate from a typical Spitz nevus, yet are insufficient for a definiti...

Nevus spilus is a melanocytic cutaneous lesion consisting of a light brown background macule with numerous superimposed darker maculopapular speckles. Melanoma arising from a nevus spilus is rare, with less than 40 cases reported to date. The absolute risk for malignant transformation is not well defined, lacking a standardized management approach. We report a new case of melanoma arising from ...

Because spitzoid melanoma shares many histopathologic features with Spitz nevus, it is one of the most difficult lesions to diagnose in dermatopathology. Uncertainty exists in the medical literature about how to diagnose melanocytic proliferations including Spitz nevus and spitzoid melanoma. A misdiagnosis of a melanoma as Spitz nevus is one of the most frequent causes of malpractice lawsuits i...

The paper presents the coexistence of a nevus flammeus and basal cell carcinoma affecting the left upper lid of 61-year-old farmer with Sturge-Weber syndrome. The occurrence of basal cell carcinoma in nevus flammeus is extremely rare. The etiology of the malignancy in this situation is unknown. It is difficult to diagnose neoplastic transformations that could arise in the nevus flammeus. Radiot...

A 19-year old female with blue rubber bleb nevus syndrome. Endoscopic laser photocoagulation and surgical resection of gastrointestinal angiomata. cerebellum: a case report and review of the literature. 39. Hofhuis WJD, Orange AP, Bouquet J, et al. Blue rubber blue nevus syndrome: report of a case with consumption coagulopathy complicated by manifest thromboses. A case report: pregnancy complic...

BACKGROUND Three cases of pointillist nevus, which is a distinctive clinical type of benign melanocytic nevus with variegated pigment, have been described in the literature to date. OBSERVATIONS A 24-year-old man presented with an acquired melanocytic lesion composed of multiple tiny pigmented dots. Dermoscopy revealed multiple brown globules on a reddish skin-colored background, and histolog...

Woolly hair nevus is a rare condition characterized by a structural anomaly of the hair, restricted to certain areas of the scalp. The hair becomes coiled and slightly hypopigmented. The term woolly hair refers to changes that affect all the scalp and has a hereditary character. We present a case of woolly hair nevus, that developed at the age of 2 years, associated with dental diastema and ver...

The predisposition to epithelial neoplasms in nevus sebaceous is well established; most tumors occur in adults and are benign. Hidradenoma is a relatively rare benign tumor of sweat gland origin that can rarely arise within a nevus sebaceous. We present an interesting case of a hidradenoma and sebaceoma arising within a nevus sebaceous and present a literature review of the 2 conditions. Even t...

Malignant melanoma and basal cell carcinoma are more common over a preexisting nevus. But squamous cell carcinoma over a nevus is a rare phenomenon. A 55-year-old male presented with a slow growing noduloulcerative lesion on a preexisting nevus over scalp. For that he had undergone excisional biopsy. Biopsy came out to be a squamous cell carcinoma with lateral margin positive for tumor. So post...

absract intracranial invasion of cellular blue nevus (cbn) from the skin is extremely rare and such a condition with malignant transformation is even rarer. a case of meningeal melanoma with malignant transformation which was derived from an ota nevus is presented in this report. a21-year-old man with a neurocutaneous syndrome since childhood was referred with headache and mild left hemiparesia...