A 38-year-old male was admitted to our hospital due to painful swelling of his right popliteal fossa. He had been kicked in his right popliteal fossa during a soccer game about three weeks earlier. Computerized tomographic angiography of the lower extremity demonstrated a 4-cm-wide, 3-cm-long aneurysmal change of the popliteal artery. He underwent aneurysmectomy and graft interposition using a ...

Uninterrupted sitting blunts vascular endothelial function in the lower extremities; however, the factors contributing to this impairment remain largely unknown. Herein, we tested the hypothesis that prolonged flexion of the hip and knee joints, as it occurs during sitting, and associated low shear stress and disturbed (i.e., turbulent) blood flow caused by arterial bending, impairs endothelial...

Introduction The aim of this study was to investigate the rate and determinants of popliteal artery aneurysm (PAA) growth in a cohort of patients with multianeurysmal disease. Methods Following a retrospective review of all patients who underwent PAA repair at a tertiary centre between 2006-2012, 22 popliteal arteries in 18 patients were identified for PAA growth study. In total, 154 duplex ult...

Prolonged sitting impairs endothelial function in the leg vasculature, and this impairment is thought to be largely mediated by a sustained reduction in blood flow-induced shear stress. Indeed, preventing the marked reduction of shear stress during sitting with local heating abolishes the impairment in popliteal artery endothelial function. Herein, we tested the hypothesis that sitting-induced ...

Case Summary. A popliteal artery entrapment syndrome and subsequent bypass surgery could cause severe, hard, fibrous occlusion of the native popliteal artery. Endovascular therapy that opens the native vessel is important to keep patency. It was impossible to advance the antegrade wire, as the entry of the native artery was not found by angiography or intravascular ultrasound imaging, making re...

Reported here is a case of bilateral high - origin anterior tibial arteries as detected during routine dissection of a 40 years old male cadaver at the Kathmandu University School of Medical Sciences, Kavre District, Nepal. The aim of the present study was to underline the clinical importance of high origin of anterior tibial artery from the popliteal artery.The high origin anterior tibial arte...

We and others have recently reported that prolonged sitting impairs endothelial function in the leg vasculature; however, the mechanism(s) remain unknown. Herein, we tested the hypothesis that a sustained reduction in flow-induced shear stress is the underlying mechanism by which sitting induces leg endothelial dysfunction. Specifically, we examined whether preventing the reduction in shear str...

Although rare, aneurysms of the infrapopliteal arteries are commonly associated with trauma. However, the combination of bilateral popliteal aneurysm with true bilateral aneurysms of the posterior tibial arteries has not been previously described. Here, as well as reviewing the relevant literature, we report the clinical and radiological aspects, and the surgical management of a 60-year-old man...

Arterial complications following arthroscopic anterior cruciate ligament (ACL) reconstruction of the knee are rare. Injuries to vascular structures around the knee have historically been reported more commonly, with reconstructive procedures occurring more posteriorly, such as posterior cruciate ligament (PCL) reconstruction. The authors present a report of sequelae following a postoperative po...

Vanilloid type 1 (VR-1) receptors are stimulated by capsaicin and hydrogen ions, the latter being a by-product of muscular contraction. We tested the hypothesis that activation of VR-1 receptors during static contraction contributes to the exercise pressor reflex. We established a dose of iodoresinaferatoxin (IRTX), a VR-1 receptor antagonist, that blocked the pressor response to capsaicin inje...