STUDY QUESTION Is there a relationship between ovarian reserve, quantified as ovarian response to stimulation, and miscarriage rate following IVF treatment? SUMMARY ANSWER There is a strong association between the number of oocytes retrieved and miscarriage rate following IVF treatment, with the miscarriage rate decreasing with an increasing number of oocytes and then levelling off: poor resp...

To the editor: I read with great interest the article by Menczer et al. [1] on the outcome prediction before neoadjuvant chemotherapy (NAC) in ovarian cancer. In the study, the authors indicated that progression free survival (PFS) of ovarian cancer patients who underwent NAC was not different between marked improvement group and no/some improvement group. The median PFS of the two groups were ...

minimal stimulation in vitro fertilization (mini-ivf) consists of a gentle controlled ovarian stimulation that aims to produce a maximum of five to six oocytes. there is a misbelief that mini-ivf severely compromises pregnancy and live birth rates. an appraisal of the literature pertaining to studies on mini-ivf protocols was performed. the advantages of minimal stimulation protocols are report...

BACKGROUND Management of women with reduced ovarian reserve or poor ovarian response (POR) to stimulation is one of the major challenges in reproductive medicine. The primary causes of POR remain elusive and oxidative stress was proposed as one of the important contributors. It has been suggested that focus on the specific subpopulations within heterogeneous group of poor responders could assis...

BACKGROUND Diminished ovarian reserve has become a major cause of infertility. Anti-Mullerian hormone (AMH) seems to be a promising candidate to assess ovarian reserve and predict the response to controlled ovarian hyperstimulation (COH). This prospective study was conducted to evaluate the relevance of AMH in a routine IVF program. METHODS Three hundred and sixteen patients were prospectivel...