Composed of up to 1,000 phospho-anhydride bond-linked phosphate monomers, inorganic polyphosphate (polyP) is one of the most ancient, conserved, and enigmatic molecules in biology. Here we demonstrate that polyP functions as a hitherto unrecognized chaperone. We show that polyP stabilizes proteins in vivo, diminishes the need for other chaperone systems to survive proteotoxic stress conditions,...

tally discovered during screening esopha− gogastroduodenoscopy in a 72−year−old woman. The polyp, located in the second portion of the duodenum, had a long stalk and a large head. Its removal was consid− ered to be technically demanding be− cause the head of the polyp occluded the lumen of the duodenum, making it diffi− cult to maneuver the snare over the polyp. The stalk part of the polyp, how...

background: abnormal uterine bleeding is a common presentation of uterine abnormalities among premenopausal and postmenopausal women. objective: to evaluate and compare the diagnostic accuracy of saline contrast sonohysterography and hysteroscopy for detecting the cause of abnormal uterine bleeding. materials and methods: a total of 65 women with abnormal uterine bleeding were enrolled in this ...

Hairy polyp is a rare, benign tumor that frequently localizes in the nasopharynx and oropharynx. The embryogenesis of hairy polyp is not known precisely. The clinical profile can vary depending on the size and location of the tumor. In this report, we present a case with hairy polyp who was admitted with acute otitis media and completely recovered after spontaneous autoamputation.

postpolypectomy bleeding and perforation are the major complications of colonoscopy. this report presents a rare case of colon obstruction immediately after colonoscopy. a 56-year-old man underwent colonoscopy because of 6 months lower abdominal pain. colonoscopy revealed diverticulosis and multiple small sessile polyps in sigmoid colon. biopsy samples were taken from the polyps and the procedu...

BACKGROUND Brunner's gland hamartoma is a rare tumor, predominantly found in the fifth to sixth decades of life. Generally, it is a single pedunculated polyp, rarely larger than 5 cm. Asymptomatic cases are found incidentally, but cases with a large polyp tend to have gastrointestinal bleeding and/or obstructive symptoms. Polyp size increases in a time-dependent manner, however, the growth mech...

pharyngeal teratomas are rare. we present a mature solid teratoma (so called “hairypolyp”) involving naso- and oro- pharynx in a female infant who presented with a gradually enlarging mass at the roof of the mouth since birth. the pharyngeal mass was protruding into the mouth through a palatine defect present posteriorly which was removed completely. subsequently she developed malposed anterior...

Choanal polyps are a form of nasal polyps that grow toward the choana with a single stalk. Septochoanal polyp is a rare entity that originates from the mucosa of the nasal septum with choanal extension. The most common site of its origin is mainly the superior aspect of the posterior portion of the nasal septum. However, metaplastic ossification is a rare event in nasal polyp and to the best of...

Objective: Explore the practical clinical significance and correlation of voice handicap index (VHI) for vocal polyps and vocal nodules, and further validate practicality of VHI. Methods: VHI of vocal cord polyp group (n = 35), vocal nodule group (n = 29), and control group (n = 22) was surveyed respectively. The VHI investigation included three categories of function (F), physiology (P) and em...

Low folate status is a risk factor for colon carcinogenesis; mechanisms proposed to account for this relationship include uracil misincorporation into DNA and global DNA hypomethylation. We investigated whether such biomarkers are related to folate status in isolated colonocytes from colonoscopy patients. In cases with adenomatous polyps (n = 40) or hyperplastic polyps (n = 16), colonocytes wer...