In gene therapy, how genetic therapeutics can be efficiently and safely delivered into target tissues/cells remains a major obstacle to overcome. To address this issue, nanoparticles consisting of non-covalently coupled polyethyleneimine (PEI) and folic acid (FA) to the magnetic and fluorescent core/shell of Fe3O4@SiO2(FITC) was tested for their ability to deliver Notch-1 shRNA. Our results sho...

Large-scale polymeric additive manufacturing (AM) is emerging as a method for producing prototype tooling in the aerospace industry. However, material options oven/autoclave-capable are currently limited to costly thermoplastics such polyetherimide (PEI) and polyphenylene sulfide (PPS). Photopolymers can be formulated oven/autoclave use have advantages over ambient processing rapid curing under...

Nanoporous polymer films have been prepared using immiscible blends of polyetherimide (PEI) and poly(caprolactone diol) (PCLD). The films were prepared by spin-coating from a common solvent – dichloromethane (DCM). To create the nanoporous films, PCLD was removed by immersing the films in acetone, which dissolves PCLD only. Field emission scanning electron microscopy was used to study the porou...

October 23-27, 2011 Gatlinburg, TN page 8 of 45 17th Symposium on Separation Science and Technology for Energy Applications agents for human applications are being developed. Toward this goal, we are testing in vivo efficacy of Cuprimine and Syprine therapeutics, that are approved by the U.S. FDA to treat copper overload in Wilson Disease (a genetic defect in copper metabolism and transport), f...

This study concentrates on radiation-induced ageing effects of polymers planned as insulating materials in the rapidly cycling superconducting magnets presently being developed for the FAIR facility. Although beam control and minimization of beam losses will be a major issue, the exposure of insulating parts (e.g. polyimide, polyetherimide, and glassenforced epoxy-compounds) of various accelera...

Within the past decades, there has been increasing interest in alternative fuels in the aviation industry. However for these alternative fuels to be accepted they must show they do not affect materials, particularly elastomers, in aircraft significantly different than standard 100 low lead (100LL). This research is focused on comparing the effects of a proprietary bio-derived alternative fuel o...