Background. Polycystic ovary syndrome (PCOS) is the most common endocrine disorder affecting 10-15% of women reproductive age. PCOS often associated with metabolic disorders, type 2 diabetes, cardiovascular disease, and other complications. In recent years, angiogenesis has been widely discussed as an important factor in pathogenesis PCOS. Objective. To identify growth factors compared healthy ...

Polycystic ovary syndrome (PCOS) is one of the most common endocrine disorders; it is characterized by polycystic ovaries, hyperandrogenism and chronic anovulation. To obtain a global view of those genes that might be involved in the development of this complex clinical disorder, we used recently developed cDNA microarray technology to compare differential gene expressions between normal human ...

Background: Polycystic ovary syndrome (PCOS) is a very common reproductive endocrine disorder. Altered cardiovascular autonomic modulation and oxidative stress may predispose PCOS patients to cardiac events in the long term. Objective: To assess relationship between sympathetic reactivity with polycystic syndrome. Methods: This cross-sectional study was conducted Department of Physiology, Banga...

A better understanding of the different phenotypes and of their endocrine and metabolic characteristics permits investigators to distinguish three main androgen excess disorders: classic polycystic ovary syndrome (PCOS), mild ovulatory PCOS, and idiopathic hyperandrogenism. These androgenic phenotypes differ more for the severity of the endocrine and metabolic alteration than for the etiopathog...

Objectives: The purpose of this review is to provide an overview existing studies on the specificities gene expression in endometrium PCOS and possible molecular mechanisms linking those with reproductive obstetric consequences PCOS. Mechanism: Polycystic ovary syndrome (PCOS) a complex disorder combining features reproductive, metabolic, psychological disturbances. effect inflammatory, endocri...

Polycystic ovary syndrome (PCOS), the most common endocrine disorder among women of reproductive age, is characterized by the coexistence of hyperandrogenism, ovulatory dysfunction, and polycystic ovaries (PCO). PCOS also represents the largest part of female oligoovulatory infertility, and the management of ovulatory and menstrual dysfunction, comprises a third of the high costs of PCOS treatm...

The polycystic appearance of the ovary is the distinguishing characteristic of polycystic ovary syndrome (PCOS) but there is a wide range of other clinical and biochemical features, e.g. elevated serum concentrations of androgens, insulin, LH and decreased insulin sensitivity. The high prevalence of affected individuals and the wide range of related phenotypes can be explained by the interactio...

Polycystic ovary syndrome (PCOS) is characterized by hyperandrogenism and chronic anovulation, and it is one of the most common endocrine disorders, affecting 5% to 10% of reproductive age women [1]. Although the etiology of the syndrome is complex, insulin resistance and hyperinsulinemia are thought to play a major role in the pathophysiology of PCOS. Insulin resistance is thought to be caused...