Purpose: Polycystic Ovary Syndrome (PCOS) is a complex multifactorial endocrine metabolic disorder of reproductive-aged women characterized by hyperandrogenism, hirsutism, anovulation, hyperinsulinemia and polycystic ovaries. The main aim this study was to investigate the association eNOS STAT6 gene Single Nucleotide Polymorphisms (SNPs) with susceptibility PCOS in South Indian Women. Research ...

In a study of 102 women (Arabs and Asians) with hirsutism, polycystic ovary syndrome was diagnosed in 93 patients (91%) including 26 cases with hirsutism and regular menstrual periods. In more than half of the cases the diagnosis was made on the basis of transabdominal ultrasonography, which was the single test with the highest yield. Luteinising hormone hyperresponsiveness to gonadotropin-rele...

Androgen receptor (AR) modulation in human uteri and ovaries of long term androgen-treated transsexual female patients was investigated. Androgen receptor expression was evaluated immunohistochemically in the ovaries of 11 and the endometria and myometria of six androgen-treated transsexual female patients. This was compared with AR expression in the ovaries and uteri of premenopausal and postm...

IntroductionPolycystic ovaries in adolescent girls with irregular periods are most commonly associated insulin resistance and hypergonadism within the PCOS. In rare instances, these findings may be caused by other underlying disorders (1,2).Case presentationA 16-year-old girl was admitted to endocrinology department due polyuria, polydipsia, weight loss. Irregular presented at age of 12, hirsut...

Polycystic ovary syndrome (PCOS) affects 6–10% of women of reproductive age and is a common cause of infertility [1]. Its clinical manifestations can include menstrual irregularities, signs of androgen excess, and obesity [1]. Trials focusing on pregnancy as an outcome may place greater emphasis on anovulation as the identifying symptom, rather than the presence of polycystic ovaries or clinica...