We introduce an adaptive search technique that speeds up state space search by learning heuristic censors while searching. The censors speed up search by pruning away moTe and more of the space until a solution is found in the pruned space. Censors are learned by explaining dead ends and other search failures. To learn quickly, the technique over-generalizes by assuming that certain constraints...

dracocephalum kotschyi boiss. is a traditional medicine with antispasmodic activities. the objective of this research was to study antispasmodic activities of hydroalcoholic extract of d. kotschyi on rat isolated uterus contractions for comparison with isolated ileum. hydroalcoholic extract was obtained from aerial part of d. kotschyi using percolation method. a portion of rat ileum or uterus w...

genus peucedanum belongs to the subfamily of apioideae (umbelliferae family) and is reported to have many medicinal properties. several spiecis of peucedum reported to have antispasmodic activity. p eucedanum pastinacifolium species grows in iran. however, so far there is no report on its antispasmodic activity. the objective of this research was to investigate antispasmodic activities of p. pa...

seeds of moringa peregrina (forssk.) fiori. (moringaceae) is widely used in south east of iran for gastrointestinal disorders. however, so far there is no pharmacological evidence for antispasmodic activity of this plant extract. therefore, the aim of this research was to investigate antispasmodic activity of m. peregrina on rat isolated ileum contraction. hydroalcoholic extract was obtained by...

a series of 3-hydroxypyridin-4-one derivatives (hpos) were synthesized and their partition coefficient values (k part ) were determined. the cytotoxic effects of these iron chelators against hela cancer cells were also evaluated. the ic 50 of hpos was determined using mtt assay. among these ligands, compound 4e (k part =5.02) with an ic 50 of 30 µm and 4f (k part =0.1) with an ic 50 of 700 µm s...

in this study, microspheres containing estradiol valerate were prepared by solvent evaporation method using poly (glycolide-co-lactide) (plga 50:50) and poly (lactide). the effect of different process variables such as polymer type, drugpolymer ratio, stirring rate, volume of internal phase and temperature of external phase on the morphology, particle size distribution, encapsulation efficiency...

peripheral nerve injuries caused by traffic accidents, resections of tumors or iatrogenic side effects of the surgeries are few of the most common form of trauma occurring with up to 500,000 cases each year in iran. conventional strategies including nerve coaptation, and the application of autografts, allografts and xenografts are restricted due to the limited availability of donors, immune-rej...