Interleukin-1beta (IL-1) is a pro-inflammatory cytokine that has been implicated in the regulation of nonrapid eye movement (nonREM) sleep. IL-1, IL-1 receptors and the IL-1 receptor antagonist (ra) are present normally in discrete brain regions, including the preoptic area (POA) of the hypothalamus and the adjoining magnocellular basal forebrain (BF). The POA/BF have been implicated in the reg...

The Generalized Second Price auction (GSP) has been widely used by search engines to sell ad slots. Previous studies have shown that the pure Price Of Anarchy (POA) of GSP is 1.25 when there are two ad slots and 1.259 when three ad slots. For the cases with more than three ad slots, however, only some untight upper bounds of the pure POA were obtained. In this work, we improve previous results ...

The present review article deals with the distribution, morphology, habitat, ecology, threat, and conservation status of Ceropegia anjanerica Malpure et al., in around Nasik district. genus L. belongs to subfamily Asclepiadoideae (milk weeds) within thefamily Apocynaceae. A total 6 species 2 varieties this have been recorded district viz., C. Malpure; Kamble Yadav, bulbosa Roxb. var. bulbosa, l...

Developmental exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) interferes with masculinization and defeminization of male sexual behaviors and gonadotropin release patterns. We previously demonstrated that the mRNA encoding the arylhydrocarbon receptor (AhR), a protein that mediates TCDD effects, is found in brain regions that control reproductive functions, most notably in the preoptic a...

BACKGROUND The Agency for Healthcare Research and Quality (AHRQ) Patient Safety Indicators (PSIs) provide information on hospital risk-adjusted rates for potentially preventable adverse events. Although designed to work with routine administrative data, it is unknown whether the PSIs can accurately distinguish between complications and pre-existing conditions. The objective of this study is to ...

BACKGROUND IVF outcomes in Chinese women are inferior to those of Caucasian patients. Reflecting prematurely diminished ovarian function, women with elevated age-specific baseline (b-) FSH levels are designated to suffer from premature ovarian aging (POA). We investigated if the prevalence of POA differs between these two ethnic populations. METHODS We compared patient characteristics and fir...

The integration of interneuron subtypes into specific microcircuits is essential for proper cortical function. Understanding to what extent interneuron diversity is regulated and maintained during development might help to reveal the principles that govern their role as synchronizing elements as well as causes for dysfunction. Particular interneuron subtypes are generated in a temporally regula...

Using the Reverse Transcription-Polymerase Chain Reaction (RT-PCR) technique, the gonadotropin releasing-hormone (GnRH) mRNA and GnRH receptor (GnRH-R) mRNA were analyzed in the preoptic area (POA), anterior (AH) and ventromedial (VM) hypothalamus, stalk/median eminence (SME) and anterior pituitary gland (AP) of anestrous ewes subjected to short or prolonged footshock stimulation. No GnRH gene ...

SiO2/SiC interface was investigated with high spatial resolution by super-higher-order scanning nonlinear dielectric microscopy (SHO-SNDM). Comparison of non-oxidized and thermally oxidized 4H-SiC wafer revealed that only 5 minutes oxidation makes the interface quality spatially inhomogeneous. SiC wafers with and without post oxidation annealing (POA) in NO ambient were also compared, which sho...

Sexual dysfunction and cognitive deficits are markers of the aging process. Mammalian sirtuins (SIRT), encoded by sirt 1-7 genes, are known as aging molecules which are sensitive to serotonin (5-hydroxytryptamine, 5-HT). Whether the 5-HT system regulates SIRT in the preoptic area (POA), which could affect reproduction and cognition has not been examined. Therefore, this study was designed to ex...