OBJECTIVE To assess prevalence of plexiform neurofibroma in children and adolescents with type I neurofibromatosis and its malignant potential. METHODS A retrospective study was conducted through analysis of the database at Centro Nacional de Neurofibromatose [Brazilian Neurofibromatosis Center], collected from the following reference services between 1996 and 2004: Instituto de Dermatologia ...

The serotonin (5-HT) innervation of the cerebral cortex in two species of lizards has been studied. Results show no differences between both species. Most of the cerebral cortex of these lizards is innervated by serotoninergic fibers, which are fine and varicose. Their density varies greatly from one cortical region to another: the areas with higher density of serotoninergic fibers and terminal...

Ameloblastoma, a benign epithelial odontogenic tumor, is locally aggressive. This tumor comprises about 1% of tumors and cysts arising in the jaws. It appears most commonly in the third to fifth decades and with equal frequency between sexes. Ameloblastoma prevalently occurs in the mandibular molar and the ramus areas. Recurrence frequently appears after inadequate treatment. They are usually b...

A neuron of the inner nuclear layer (INL) with some processes extending to the outer plexiform layer (OPL) and others to the inner plexiform layer (IPL) was discovered near the posterior pole of the mouse retina. The neuron's location and appearance are similar to the interplexiform cells of several other species. The relatively recent recognition of this cell type along with its characteristic...

We have correlated the membrane properties and synaptic inputs of interplexiform cells (IPCs) with their morphology using whole-cell patch-clamp and Lucifer yellow staining in retinal slices. Three morphological types were identified: (a) a bistratified IPC with descending processes ramifying in both sublaminas a and b of the inner plexiform layer (IPL), and an ascending process that branched i...

a 64-year-old male presented with neurofibromatosis 1 and cushing’s syndrome. clinically he was over weight, depressed with extensive skin bruising and hypertension. his 24 hours urinary metanephrines, urinary 5hiaa, gut peptides and chromgranin levels were normal. his renal function and renal mri scan was also normal. his cortisol failed to suppress on overnight dexamethsone suppression test. ...

Ameloblastoma is an uncommon epithelial odontogenic neoplasm that is nonmineralized, locally aggressive, and, in most cases, benign. Most ameloblastomas develop in the molar-ramus region of the mandible with 70% of them arising in the molar-ramus area. Radiologically they are unilocular or multilocular radiolucency with a honeycomb or soap bubble appearance. The radiographic appearance of amelo...

Expression of synaptophysin, synapsin I and syntaxin was studied immunocytochemically in the developing rat retina using indirect immunoperoxidase technique. In the inner plexiform layer (IPL), syntaxin immunoreactivity appeared at postnatal day 1 (P1) whereas synaptophysin and synapsin I staining were first observed at P2. In the outer plexiform layer (OPL), synaptophysin appeared at P4, while...

1Department of Neurosurgery, Restauração Hospital, Recife PE, Brazil; 2Department of Neurology, Hospital Getúlio Vargas, Recife PE, Brazil; 3Department of Nursing, Restauração Hospital, Recife PE, Brazil; 4Department of Radiology, Restauração Hospital, Recife PE, Brazil. Correspondence: Fernando Henrique Souza; Departamento de Neurocirurgia, Hospital da Restauração; Avenida Agamenon Magalhães s...

Neurofibromas are benign tumours arising from neurons andperineural cells. Although they are common inneurofibromatosis, occasionally solitary neurofibromas may occur. A rare case of solitary neurofibroma presenting as a giant gluteal mass in a male patient without a personal or family history of neurofibromatosis is presented. Pre-operative imaging gave useful information about the extent of t...