Fractionation of petroleum ether partitioned ethanol extract and crude petroleum ether extract of the leaves of Murraya koenigii Linn (Rutaceae) led to the isolation of 5,8-dimethyl furanocoumarin (1) and 1-al, 3[6’, 6’ dimethyl 5-hexene] carbazole (2) and β-sitosterol (3). Their structures were elucidated by spectroscopic methods such as UV, IR, NMR and LCMS. All the compounds were isolated fo...

Andrographis macrobotrys Nees is an extensively utilized Indian traditional medicine to treat several human and livestock disorders. The present investigation was designed to evaluate the antibacterial, antifungal potentialities and phytochemical screening of the different leaves and stem extracts of Andrographis macrobotrys belongs to the family Acanthaceae. Methanol, ethanol, chloroform, acet...

Andrographis alata Nees is an important medicinal plant. The current study was to investigate the antibacterial, antifungal activity and phytochemical analysis of the various leaf and stem extracts of A.alata. Methanol, ethanol, chloroform, acetone and petroleum ether extracts of shade dried plant leaf and stem of A.alata were tested for antibacterial, antifungal and phytochemical screening. Th...

The rising problem of resistance to most commonly used antimalarials remains a major challenge in the control of malaria suggesting the need for new antimalarial agents. This work explores the antiplasmodial potential of ethanol extract of Russelia equisetiformis in chloroquine Plasmodium berghei infected mice. Swiss albino mice were intraperitoneally infected with chloroquine-resistant P. berg...

Acanthopanax trifoliatus (L) Merr (AT) is commonly used as an herbal medicine and edible plant in some areas of China and other Asian countries. AT is thought to have anticancer effects, but potential mechanisms remain unknown. To assess the anticancer properties of AT, we exposed prostate cancer cells to AT extracts and assessed cell proliferation and signaling pathways. An ethanol extract of ...

This study aimed to evaluate the in vitro and in vivo leishmanicidal activity of an endemic Turkish plant and compare its efficacy with a reference drug. In addition to the in vitro activities of the ethanol, acidified and alkaloid extracts and furoquinoline alkaloids skimmianine and gamma-fagarine, in vivo antileishmanial activitiy of the acidified extract of Haplophyllum myrtifolium Boiss. (R...

Ethnopharmacological relevance: The dry leaf of Alchornea cordifolia (AC) is used, in traditional medicine in the S Nigeria, for the preparation of blood tonic, remedies for urinary, respiratory, liver and gas intestinal disorders. Aim of the study: This study investigated the protective property of AC leaf against liver damage in animals with a view to exploring its use for the treatment of he...

The current study included the preparation of the aqueous extract and alcohol leaves Ziziphus (Ziziphus spinachristi), Eucalyptus plant (Eucalyptus camaldulensis) and assessed the antimicrobial its against reference strains of bacteria and mold, through chemical compound detection leaves Ziziphus plant results showed contain the aqueous extract and alcohol at all effective compounds that have b...

Melastoma malabathricum (MM) is a well-known plant in Malaysian traditional medicine, locally known as senduduk. Its ethanol and aqueous extracts have been used in the present investigation to study the immunomodulatory role on human peripheral blood mononuclear cell (PBMC), and the DPPH, ABTS and FRAP free radical scavenging activities were also measured. Total flavonoids and total phenolic co...

Objective: Vernonia amygdalina (V.  amygdalina) leaf is locally employed in the Southern region of Nigeria in the treatment of malari a infection. This study evaluated the in vivo antiplasmodial, antioxidant and immunomodulatory effect of ethanol extract of V.  amygdalina leaf. Materials and Methods: The active principles of the dried leaf were extracted with ethanol. For quality validation, ch...