Thrombophilic risk factors are common and can be found in 15% to 25% of Caucasian populations. Since pregnancy is an acquired hypercoagulable state, women harboring thrombophilia may present with clinical symptoms of vascular complications for the first time during gestation or at the postpartum period(1). Women with thrombophilia may have an increased risk of placental vascular complications, ...

OBJECTIVE The aim of this study was to identify the relevant obstetric factors for cerebral palsy (CP) after 33 weeks' gestation in Japan. STUDY DESIGN This retrospective case cohort study (1:100 cases and controls) used a Japanese national CP registry. Obstetric characteristics and clinical course were compared between CP cases in the Japan Obstetric Compensation System for Cerebral Palsy da...

OBJECTIVE To compare the incidences of preterm delivery, cervical incompetence treated by cerclage, placental implantation or retention problems (ie, placenta praevia, placental abruption and retained placenta) and postpartum haemorrhage between women with and without a history of pregnancy termination. DESIGN  A retrospective cohort study using aggregated data from a national perinatal regis...

Placental dysfunction is involved in a group of obstetrical conditions including preeclampsia, intrauterine growth restriction, and placental abruption. Their timely and accurate recognition is often a challenge since diagnostic criteria are still based on nonspecific signs and symptoms. The discovering of the role of angiogenic-related factors (sFlt-1/PlGF) in the underlying pathophysiology of...

<b><i>Introduction:</i></b> Twin-twin transfusion syndrome (TTTS) is a complication in monochorionic twin pregnancies which preferably treated with fetoscopic laser surgery. A few small studies suggested possible association between the Solomon technique and placental abruption. <b><i>Methods:</i></b> The objective of this study to compare rate ex...

In the UK, hemorrhage was the major factor in more than 150 maternal deaths between 1985 and 19961, and remains one of the main causes of admission of pregnant women to intensive care units2–4. In countries with limited resources, the toll from obstetric hemorrhage is greater5,6 and a significant number of the deaths from hemorrhage are associated with substandard care and/or inadequate obstetr...