BACKGROUND According to Iranian traditional medicine, using safe ginger may contribute to taking less chemical medicines and result in fewer side effects. OBJECTIVE To determine the influence of using ginger before operation on nausea and vomiting, after cataract surgery under general anesthesia. METHODS This study was a double-blind placebo-controlled randomized clinical trial conducted at...

Abstract Background: Using a randomized, double blind, placebo-controlled, crossover protocol, we have shown previously that progesterone may prevent sleep disturbances but has no action on undisturbed sleep. In study, 8 healthy postmenopausal women took daily at 2300 h for 3 wk capsule of either 300 mg or placebo. Sleep was polygraphically recorded during the last two nights and, second night,...

Multilayer biodegradable polymer drug delivery, time dependent release has many exceptional advantages in controlled drug delivery system. The inception of layer by layer constructed tablet-in-capsule facilitated release of drug in accordance of stimuli response carrier system. Atorvastatin calcium and Amlodipine besylate were chosen a model drug because of its poor absorption in gastrointestin...

The fermentation of starch in vitro produces a higher proportion of butyrate than the fermentation of most other substrates. The alpha-glucosidase inhibitor acarbose increases the amount of starch entering the colon, and has been shown to increase faecal butyrate in humans. It is generally considered that colonic butyrate is quantitatively removed by the colonic mucosa and liver and does not ap...

Gut microflora dysbiosis affects the majority of individuals after COVID-19, contributing to both gastro-intestinal (GI) and non-GI symptoms. Natural phytochemicals have reported anti-viral properties favourable effects on inflammatory oxidative pathways, important for tissue damage post-viral pneumonia. This study involved 147 participants with symptomatic randomised receive a placebo (P) or p...

The efficacy and safety of Salvia officinalis combined with statin have not been evaluated in dyslipidemic diabetes mellitus type 2 (DDMT2) so far. The plant extract antioxidant activity was determined by the DPPH radical scavenging assay. The total flavonoid, total phenolic and quercetin contents of the capsules containing the plant extract were also measured. Moreover, the effects of 2-month ...

The aim of the study is to evaluate effectiveness and safety liposomal technologies in treatment non-alcoholic fatty liver disease (NAFLD) using Silybin (Lipoliv) as an example.
 Materials Methods. authors conducted a randomized placebo-controlled approved by ethics committee. included 111 subjects with NAFLD, aged 18–65. Lipoliv therapy (experimental group) or placebo (control lasted for ...

 Background: Advanced type 2 diabetes mellitus (T2DM) needing insulin therapy is a common disease. Previous studies indicate that aloe (Aloe vera L.) leaf gel may positively affect the blood glucose and lipid levels in patients with advanced T2DM needing insulin.  Objective: Evaluation of the efficacy and safety of aloe leaf gel in the treatment of type 2 diabetic patients resistant to ...

objective: cancer represents the second cause of mortality in the world. saffron as a medicinal plant is known for its anti-cancer and anti-depressant properties. in this randomized double blind clinical trial, the effects of saffron on response to treatment in patients suffering from liver metastasis were evaluated. materials and methods: thirteen patients suffering from liver metastases who r...

Requests for night sedation and the use of placebo as first line drug management were studied prospectively in 1174 consecutive elderly hospital in-patients. Of the 390 (33.2%) patients requesting sleeping pills in hospital, 37 were subsequently satisfied without the prescription of additional medication. A further 216 patients were entirely satisfied with a placebo capsule during all of their ...