Abbreviations: patent foramen ovale, PFO; transcranial Doppler ultrasonography, TCD; Global initiative for chronic Obstructive Lung Disease, GOLD; partial pressure of oxygen, PaO2; oxygen uptake, V’O2; high-intensity transient signals, HITS Funding Support: Not Applicable. Citation: Fenster BE, Carroll JD. Patent foramen ovale in COPD and hypoxia: Innocent bystander or novel therapeutic target?...

We present a seminested PCR method that specifically discriminates between Plasmodium ovale curtisi and P. ovale wallikeri with high sensitivity. The test is based on species-specific amplification of a size-polymorphic fragment of the tryptophan-rich antigen gene, potra, which also permits discrimination of intraspecific sequence variants at this locus.

1. Alushi, B., Biasco, L., Orzan, F., Omede, P., Sciuto, F., Moretti, C., . . . Gaita, F. (2014). Patent foramen ovale treatment strategy: an Italian large prospective study. J Cardiovasc Med (Hagerstown), 15(10), 761-768. doi: 10.2459/jcm.0000000000000138 2. Baglini, R., Baldari, D., Amaducci, A., & D'Ancona, G. (2013). The new patent foramen ovale occluder FIGULLA in complex septal anatomy: a...

Despite 3 recent randomized clinical trials, the management of patients with cryptogenic stroke and patent foramen ovale remains unsettled. The primary results of Evaluation of the STARFlex Septal Closure System in Patients with a Stroke and/or Transient Ischemic Attack due to Presumed Paradoxical Embolism Through a Patent Foramen Ovale (CLOSURE), Percutaneous Closure of Patent Foramen Ovale in...

A patent foramen ovale from an anatomical and physiological point of view is a normal communication between the atria, which present in utero allows oxygenated placental blood to reach fetal arterial circulation. With incomplete postpartum fusion primary secondary septa, formed. In last two decades, clinical interest problem dictated by fact that its role development such syndromes as ischemic ...

Platypnea orthodeoxia is a rare disorder characterized by dyspnea and arterial desaturation, exacerbated by the upright position and relieved when the subject is recumbent. We report the case of a 79-year old woman admitted to hospital with dyspnea who was thought to have restrictive ventilatory impairment due to osteoporosis and severe kyphosis. Interestingly, the dyspnea was aggravated in the...

The current study investigated the occurrence of ticks and their rickettsiae in the Serra do Mar State Park, which encompasses one of the largest Atlantic rain forest reserves of Brazil. From July 2008 to June 2009, a total of 2439 ticks (2,196 free living and 243 collected on hosts) was collected, encompassing the following 13 species: Amblyomma aureolatum (Pallas), Amblyomma brasiliense AragA...

Patent foramen ovale and atrial septal aneurysm are considered to be factors conducive to the occurrence of stroke and transient ischaemic attacks. However, there is no clear answer to the question whether patent foramen ovale is an independent risk factor for stroke and what the mechanism of potential cerebral ischaemia in patients with an interatrial septal abnormality is. The paper presents ...

An American physician-traveler to East Africa presented with manifestations of cerebral malaria and was treated with intravenous quinidine for chloroquine-resistant falciparum malaria. He later relapsed with Plasmodium ovale infection, despite previous primaquine therapy. Treatment of chloroquine-resistant malaria is discussed. The difficulty in diagnosing P. ovale infections and the predominan...

The aim of the study was the retrospective morphological analysis of selected structures of the middle cranial fossa, i.e. foramen ovale and superior orbital fissure, in relation to the external head and cranial diameters in adults from the Lublin region (Poland). The study was performed on data collected during computed tomography examinations of 60 individuals (age 20-30 years), without any c...