Background & Objectives:  CD10 is a cell surface enzyme with metalloendopeptidase activity, also known as Common Acute Lymphoblastic Leukaemia Antigen, which mainly serves as a marker for acute lymphoblastic leukemia (ALL). To date and to the best of our knowledge, only few comparative immunohistochemical studies have assessed CD10 expression in cutaneous epithelial neoplasms. Our goal was to d...

Background: Basal cell carcinoma (BCC) is the most common skin cancer in whites. Objective: Determination of anatomical localization of BCC in relation to histological subtypes of this tumor. Patients and methods: This survey is a descriptive cross sectional study carried out on 189 cases of BCC patients diagnosed in Hamadan Sina hospital between 1997-1999. Results: This study showed 7 hi...

Background: Surgery is the most frequent treatment modality for basal cell carcinoma but in spite of its high cure rate, the frequency of incomplete excision varies widely (0.7-50%) among dermatologic centers. Our case series was designed to determine the frequency of incompletely excised basal cell carcinoma and the related risk factors. Methods: A total of 1424 basal cell carcinoma (1040 pati...

Basal cell carcinoma (BCC) is the most common cutaneous malignancy and characterized by sustained Hedgehog (Hh) signaling. Despite major insights into molecular basis of BCC, relatively little known about how BCC tumor cells affect other types in microenvironment. It has been frequently observed that a subset tumors are clinically pigmented. Using immunostaining for melanocyte-specific antigens...

Background: Basal cell carcinoma (BCC) is the commonest malignancy among Caucasians in Europe, North America, and Australia. This study attempted to identify the prevalence, risk factors, and outcome of management of this problem in our region. Methods: All the patients with histologic diagnosis of BCC presenting to the University of Calabar Teaching Hospital, Calabar during the study period Ja...

BACKGROUND Basal cell carcinoma (BCC) is the most common malignancy with increasing incidence worldwide. The tumor invades surrounding tissues in an irregular pattern via subclinical and microscopic finger-like growths known as subclinical extension. Subclinical extension may be responsible for incomplete resection of the tumor. This study investigates the subclinical extension of BCC. METHOD...

Pigmented squamous cell carcinoma in-situ (SCCIS) is a rare variant of cutaneous SCC that can clinically mimic malignant melanoma. This more commonly seen in patients with brown and black skin often presents sun-protected areas. We report case 38-year-old man dark brown, expanding lesion on the lateral aspect left middle finger history immunosuppression secondary to chronic corticosteroid treat...