Unlike other sensory systems, the cortical organization of the human vestibular system is not well established. A central role is assumed for the region of the posterior Sylvian fissure, close to the posterior insula. At this site, activation during vestibular stimulation has been observed in previous imaging studies and labeled as the parieto-insular vestibular cortex area (PIVC). However, ves...

The formation of a stable 43 S preinitiation complex (PIC) must occur to enable successful mRNA recruitment. However, the contributions of eIF1, eIF1A, eIF3, and the eIF2-GTP-Met-tRNAi ternary complex (TC) in stabilizing the 43 S PIC are poorly defined. We have reconstituted the human 43 S PIC and used fluorescence anisotropy to systematically measure the affinity of eIF1, eIF1A, and eIF3j in t...

BACKGROUND Chloropicrin (Pic) offers a potential alternative to methyl bromide (MB) against Ralstonia solanacarum in ginger (Zingiber officinale Rosc.) production. MB is scheduled to be withdrawn from routine use by 2015 in developing countries. METHODS Pic treatments were evaluated in a laboratory study and in three commercial ginger fields. RESULTS Laboratory studies showed that the EC50 ...

MIMO-OFDM with bit-interleaved coded modulation (BICM) is an attractive technique for wireless communications over frequency selective fading channels which has gained significant interests as a promising candidate for the 4th Generation wireless communication. The SISO MMSE-PIC based detector is proposed in this paper. The SISO MMSE-PIC detector exchanges soft information with SISO channel dec...

Parallel interference cancellation (PIC) is a well-known multiuser detection algorithm in direct-sequence code-division multiple-access (DS-CDMA) systems. It is typically implemented with a multi-stage architecture. One problem associated with the PIC is that unreliable interference cancellation may occur in the early stages and the system performance may be degraded. Thus, the partial PIC dete...

P-glycoprotein (PGP), an active efflux pump of antitumor agents in multidrug-resistant tumor cells, exists in brain capillary endothelium and could be functionally involved in the blood-brain barrier. To study the regulatory mechanism of PGP expression in brain capillary endothelium, various mouse tissue matrices were tested for their abilities to enhance the expression of PGP in mouse brain ca...

Neuromodulatory inputs from brainstem systems modulate the normal function of spinal motoneurons by altering the activation properties of persistent inward currents (PICs) in their dendrites. However, the effect of the PIC on firing outputs also depends on its location in the dendritic tree. To investigate the interaction between PIC neuromodulation and PIC location dependence, we used a two-co...

BACKGROUND The cementation of fixed implant-supported dental restorations involves the risk of leaving excess cement in the mouth which can promote biofilm formation in the peri-implant sulcus. As a result, an inflammation may develop. PURPOSE The aim of the present study was to investigate the clinical effect of two different luting cements on the peri-implant tissue. MATERIALS AND METHODS...

PURPOSE Photoimmunotherapy may allow target-specific photodynamic destruction of malignancies and may also potentiate anticancer antibody therapies. However, clinical use of either of the two modalities is limited for different reasons. Antibody therapies suffer from being primarily cytostatic and the need for prolonged administration with consequent side effects. In the case of photoimmunother...