We examined the physiological response of foliage in the upper third of the canopy of 125-year-old giant sequoia (Sequoiadendron giganteum Buchholz.) trees to a 61-day exposure to 0.25x, 1x, 2x or 3x ambient ozone concentration. Four branch exposure chambers, one per ozone treatment, were installed on 1-m long secondary branches of each tree at a height of 34 m. No visible symptoms of foliar oz...

Purpose: To study the relationship between (FDG) uptake expressed quantitatively as standardized uptake values (SUVs) in normal breast tissues and breast density, age, menopausal status determined during dual-time point FDGPET/CT imaging. Materials and Methods: maximum and average SUVs were determined in two hundred eighty four patients (all females; mean age 55.5 ± 14.1 range 13-84 years, 115 ...

Pinocytic uptake of 125I-labeled bovine serum albumin by 17.5-day rat visceral yolk sac cultured in vitro has been examined. Uptake was followed by intracellular digestion and, after an initial period, the content of radioactivity in the tissue itself remained constant during the incubation. Radiolabel was returned to the culture medium predominantly as (125I)iodotyrosine; exocytosis of undiges...

In humans and animals lacking functional LDL receptor (LDLR), LDL from plasma still readily traverses the endothelium. To identify the pathways of LDL uptake, a genome-wide RNAi screen was performed in endothelial cells and cross-referenced with GWAS-data sets. Here we show that the activin-like kinase 1 (ALK1) mediates LDL uptake into endothelial cells. ALK1 binds LDL with lower affinity than ...

Calcium balance is essential for a multitude of physiological processes, ranging from cell signaling to maintenance of bone health. Adequate intestinal absorption of calcium is a major factor for maintaining systemic calcium homeostasis. Recent observations indicate that a reduction of gastric acidity may impair effective calcium uptake through the intestine. This article reviews the physiology...

the impacts of salicylic acid and silicon on some physiological parameters of maize seedlings in the presence ofcadmium (100 μm) were investigated. inhibitory effects of cadmium on seedling growth resulted in reduced shoot and root fresh weight, low percentage of relative water content, low chlorophyll, free proline and soluble sugars contents and a low rate of lipid peroxidation. results indic...

To probe the mechanism by which intracellular ATP, Na+, and Cl- influence the activity of the NaK2Cl cotransporter, we measured bumetanide-sensitive (BS) 86Rb fluxes in the osteosarcoma cell line UMR-106-01. Under physiological gradients of Na+, K+, and Cl-, depleting cellular ATP by incubation with deoxyglucose and antimycin A (DOG/AA) for 20 min at 37 degrees C reduced BS 86Rb uptake from 6 t...

We have previously demonstrated that dietary histamine is accumulated in the spleens of l-histidine decarboxylase (HDC)-deficient mice, which lack endogenous histamine synthesis. To characterize the clearance system for dietary histamine in mice, we investigated the cell type and mechanism responsible for histamine uptake in the spleens of HDC-deficient mice. Immunohistochemical analyses using ...

The uptake of the unnatural amino acid alpha-aminoisobutyric acid (AIB) and glutamine by developing soybean (Glycine max Merr. cv Chippewa 64) embryos was investigated. In freshly excised embryos, the accumulation ratio (cytoplasmic concentration/external concentration) of AIB did not exceed 1.0. After an 18-hour preincubation in nitrogen-free medium the accumulation ratio of AIB exceeded 4.5 a...

The action of adrenocorticotropin (ACTH) on the specific (receptor-mediated) uptake of cholesteryl linoleate *low density lipoprotein complexes was examined in Y-l mouse adrenal tumor cells. High affinity binding (I& 4.1 x 10” M) was observed with ACTH; lower affinity was seen in the absence of ACTH. The effect of ACTH was observed within 10 min at physiological concentrations of low density li...