Multiple sclerosis (MS) is a chronic disease of the central nervous system that culminates in the progression of physical and cognitive disability over time. Walking impairment is a ubiquitous feature of MS and a sentinel characteristic of the later or advanced stages of the disease. This paper presents a conceptual rationale along with empirical evidence for exercise training as a rehabilitati...

significant advances have been made in diagnosis and therapy of demyelinating disorders of the central nervous system. the most common entities of this disorders in adults – multiple sclerosis and neuromyelitis optica were initially thought to be different phenotypes of more or less the same disease. during the last ten years, this view was subsequently changed and the term neuromyelitis optica...

dementia is defined as significant acquired cognitive impairment in one or more cognitive domains that represents a significant decline from previous baseline and interferes with independence in daily activities. autoimmune dementia is a term that has been used to describe a steroid-responsive autoimmune disorder characterized by a rapidly progressive dementia with a fluctuating course. even co...

Objectives We aimed to examine the effects of various leisure activities on cognitive impairment in young-old (aged 65-74 years) and old-old (aged ≥ 75 years) adults. Methods In total, 10,279 elderly Korean individuals from the 2014 Korean National Survey on Older Adults' cohort were enrolled in our study. Cognitive impairment was assessed using the standardized score of the Mini-Mental State...

Purpose: Sport is an important tool in improving the quality of life individuals with disabilities. The study aim to examine physical disabilities different functionality levels relation sports.
 Methods: A total 36 participated study. participants included without any regular exercise (non-sportive, NS), those who played Boccia (B), and persons Wheelchair basketball (WCB) could not provid...

OBJECTIVE To test the hypothesis that minor physical anomalies (MPAs) modify an adolescent's vulnerability to environmental risk factors for psychopathology. METHOD One hundred eighteen unreferred male adolescents who had been evaluated as 7-year-olds received a comprehensive neuropsychiatric evaluation. The evaluation included standardized assessments of environmental risk factors for psychi...

PURPOSE To assess the impact of visual impairment on health-related quality of life (HRQOL) in an older population and compare it with the impact of major medical conditions. METHODS Participants of the second cross-sectional Blue Mountains Eye Study (BMES; n = 3509; mean age, 66.7 years; 57% female) were asked to complete the self-administered 36-item Short-Form health survey (SF-36), a comp...

OBJECTIVE To evaluate cognitive outcome in adult survivors of bacterial meningitis. METHODS Data from three prospective multicentre studies were pooled and reanalysed, involving 155 adults surviving bacterial meningitis (79 after pneumococcal and 76 after meningococcal meningitis) and 72 healthy controls. RESULTS Cognitive impairment was found in 32% of patients and this proportion was simi...

We study the quantum electrodynamics vacuum in the presence of a body rotating along its axis of symmetry and show that the object spontaneously emits energy if it is lossy. The radiated power is expressed as a general trace formula solely in terms of the scattering matrix, making an explicit connection to the conjecture of Zel'dovich [JETP Lett. 14, 180 (1971)] on rotating objects. We further ...