The mechanism of FGF23 action in calcium/phosphorus metabolism of patients with chronic kidney disease (CKD) was studied using a mathematical model and clinical data in a public domain. We have previously built a physiological model that describes interactions of PTH, calcitriol, and FGF23 in mineral metabolism encompassing organs such as bone, intestine, kidney, and parathyroid glands. Since a...

Unlike Pho85 of Saccharomyces cerevisiae, the highly related PHOA cyclin-dependent kinase (CDK) of Aspergillus nidulans plays no role in regulation of enzymes involved in phosphorous acquisition but instead modulates differentiation in response to environmental conditions, including limited phosphorous. Like PHO85, Aspergillus phoA is a nonessential gene. However, we find that expression of dom...

Ankur Sinha [email protected] Department of Information and Service Economy, Aalto University School of Business PO Box 21210, FIN-00076 Aalto, Helsinki, Finland Pekka Malo [email protected] Department of Information and Service Economy, Aalto University School of Business PO Box 21210, FIN-00076 Aalto, Helsinki, Finland Kalyanmoy Deb [email protected] Department of Electrical and Computer ...

Top predators can provide fundamental ecosystem services such as nutrient cycling, and their impact can be even greater in environments with low nutrients and productivity, such as Arctic tundra. We estimated the effects of Arctic fox (Vulpes lagopus) denning on soil nutrient dynamics and vegetation production near Churchill, Manitoba in June and August 2014. Soils from fox dens contained highe...

The structure of gallium arsenide and indium phosphide (0 0 1) surfaces in the metalorganic vapor-phase epitaxy (MOVPE) environment has been investigated. During growth at V/III ratios in excess of 10, both materials are terminated with group V ad-dimers (As or P), alkyl groups and hydrogen atoms. These species sit on top of a complete layer of the group V atoms. As the V/III ratio decreases, t...

The activity and selectivity of aluminaand magnesia-supported vanadia for propane oxidative dehydrogenation can be enhanced by can be enhanced by interactions of vanadia with molydena for the alumina-supported catalyst and by phosphorous doping for the magnesia-supported catalyst.

A CBL-interacting protein kinase (CIPK) gene, BnCIPK6, was isolated in Brassica napus. Through yeast two-hybrid screening, 27 interaction partners (including BnCBL1) of BnCIPK6 were identified in Brassica napus. Interaction of BnCIPK6 and BnCBL1 was further confirmed by BiFC (bimolecular fluorescence complementation) in plant cells. Expressions of BnCIPK6 and BnCBL1 were significantly up-regula...

One of the most common types of urinary stones formed in humans and some other mammals is composed of calcium oxalate in ordered hydrated crystals. Many studies have reported a range of metals other than calcium in human stones, but few have looked at stones from animal models such as the dog. Therefore, we determined the elemental profile of canine calcium oxalate urinary stones and compared i...

The yield of triptane from the reaction of methanol with zinc iodide is dramatically increased by addition of phosphorous or hypophosphorous acid, via transfer of hydride from a P-H bond to carbocationic intermediates.

Salinity is one of the most severe abiotic stresses in one-half of all irrigated lands, causing negative effects on physiological, biochemical, and molecular responses in plants. Application of chemical fertilizers, particularly phosphorus (P) fertilizers, may reduce harmful effects of salinity. In this study, an investigation was performed on the effects of exogenous application of different l...