A new gradient reverse phase high performance liquid chromatography method has been developed for quantitative determination of related substances of Lysine Clonixinate (LC) and Cyclobenzaprine Hydrochloride (CBP) in pharmaceutical dosage forms. Chromatographic separation achieved on a column L1, C18 250 mm x 4.6 mm; 5 μm with 0.025M Potassium dihydrogen phosphate pH 3.0 buffer as mobile phase-...

1. This note summarizes a paper [4] to appear in full elsewhere. It presents an algorithm for the minimization of a general (not necessarily differentiable) convex function. Its central idea is the construction of descent directions as projections of the origin onto the convex hull of previously calculated subgradients as long as satisfactory progress can be made. Using projection to obtain a d...

A gradient reversed-phase liquid chromatographic (RP-LC) method was developed for the quantitative estimation of impurities in the pharmaceutical dosage form of Omeprazole and Domperidone capsules. The developed method is a stability-indicating test method for the estimation of impurities generated during the formulation and storage of Omeprazole and Domperidone capsules. The chromatographic se...

A simple, linear gradient, rapid, precise and stability-indicating RP-UPLC method was developed for the determination of Cloxacillin Sodium in its bulk form and formulation. Ultra performance liquid chromatography, a most promising advancement in a world of chromatography, reduces analysis time, increases reliability through higher resolution, sensitivity and selectivity as well as used as an e...

Red blood cell glucose metabolism was investigated in a male patient with de novo trisomy 10p. According to previous evidence, when assigning hexokinase gene locus in the 10p11 leads to pter region, a triplex dosage effect of hexokinase activity (HK) was found, while all the other erythrocyte glycolytic enzymes were in the normal values range. Red blood cell glucose utilization was 2.87 mumole/...

F-ATPases synthesize ATP from ADP and phosphate coupled with an electrochemical proton gradient in bacterial or mitochondrial membranes and can hydrolyse ATP to form the gradient. F-ATPases consist of a catalytic F1 and proton channel F0 formed from the alpha3beta3gammadelta and ab2c10 subunit complexes, respectively. The rotation of gammaepsilonc10 couples catalyses and proton transport. Consi...

In this paper we address the issue of recognizing Farsi handwritten words. Two types of gradient features are extracted from a sliding vertical stripe which sweeps across a word image. These are directional and intensity gradient features. The feature vector extracted from each stripe is then coded using the Self Organizing Map (SOM). In this method each word is modeled using the discrete Hidde...

phosphorus solubilizing microorganisms are capable of transforming insoluble phosphorus (p) forms to soluble and bioavailable p. the aim of the present study was to isolate p solubilizing bacteria from forest soils around the rock phosphate (rp) mine of koh-e-sepidlar in kohgiluyeh and boyer ahmad province and evaluate their ability in sperber culture medium and wheat straw medium in the presen...

Unilamellar vesicles composed of phosphatidylcholine (PC) and either phosphatidic acid (PA) or phosphatidylglycerol (PG) partition to the upper poly(ethylene glycol) (PEG)-rich phase of a charge-sensitive 5%:5% (w/w) PEG 8000/Dextran T-500 phase system containing 10 mM sodium phosphate at pH 7, consistent with the vesicles bearing a net negative charge. When prepared in the presence of a pH gra...

background: phosphorus is an indispensable element for the growth of animals and plants. there are several environmental problems related to phosphate; therefore, the technical and economic methods of removing phosphate are of great importance. this study evaluated the efficiency of polyaniline/ni0.5zn0.5fe2o4 magnetic nanocomposite in removing phosphate from aqueous environments. methods: the ...