We report the case of a 52 year old male with diabetes mellitus and long standing evidence of hepatic iron excess. Initially considered to have haemochromatosis, this patient was reevaluated when hepatic iron stores were found to be unaffected by a prolonged course of weekly phlebotomy. The development of neurological disease prompted diagnostic consideration of aceruloplasminaemia, which we co...

To study the appropriateness of phlebotomy for digoxin therapeutic drug monitoring (TDM) in outpatients, we conducted a retrospective chart review, a computer search of all previous TDM testing, and a questionnaire of all outpatients (n = 86) who had serum digoxin determinations between April 10 and April 28, 1992 (585 tests). In patients who took digoxin at the same time daily (40 patients, 30...

Blood loss associated with phlebotomy is significant in critically ill adults. Iatrogenic anemia may result and impose unnecessary stress on the cardiovascular and respiratory systems and may require allogeneic blood transfusions. Many strategies exist under nursing's direct control to decrease blood loss associated with phlebotomy. In the past, nursing effectively implemented many of these str...

The possibility of accidental injury to an artery in the course of surgical treatment has been known for centuries. Galen described an incident in which a young surgeon damaged the brachial artery in the course of phlebotomy, and commented that most such cases resulted in aneurysm. William Hunter also described arterial injury as a complication of phlebotomy. In recent years there have been a n...

The kinetics in blood of autologous neuin whole blood for 1-2 days, posttransfutrophils collected by phlebotomy, filtration sian recoveries and blood half-times were leukapheresis (FL), or intermittent-flow significantly decreased. Storage of both centrifugation (IFC), labeled with 32PIFC and FL preparations resulted in only diisopropylfluorophosphate, and stored at moderate kinetic abnormaliti...