First descriptions of diseases attract tremendous interest because they reveal scientific insight even in retrospect. Max Schottelius, the pathologist contributing the first histological description of pheochromocytoma, remains anonymous. We reviewed the description by Schottelius and weighed the report in modern context. Schottelius described the classical diagnostic elements of pheochromocyto...

Pheochromocytoma is an endocrine tumor classically presenting with headache, paroxysmal hypertension, and palpitations. We discuss the case of a young male, presenting with acute heart failure and cardiogenic shock requiring stabilization with an intra-aortic balloon pump and a combination of ionotropes and vasopressors. Pheochromocytoma was diagnosed by CT scan, as well as urine and plasma met...

Pheochromocytoma is a rare tumor, usually benign, potentially lethal in case of crisis with acute release of catecholamines. The heart is a target and the clinical presentation can mimic various cardiac conditions, thus rendering diagnosis elusive. Cardiac magnetic resonance is a valuable non-invasive diagnostic tool for the evaluation of cardiomyopathies; it allows the identification of catech...

Pheochromocytoma is a rare cause of hypertension in children. Hypertension is one of the common reasons of posterior reversible encephalopathy. Intracerebral hemorrhage is a serious and unexpected complication of hypertensive encephalopathy due to pheochromocytoma, and very rarely seen in the childhood. Intracerebral hemorrhages should be searched if there are hypertensive reversible signal cha...

We report the case of a 69 year-old Chinese lady with pheochromocytoma who developed chest pain and acute ST-segment elevation in the anterior leads on electrocardiography. She was given intravenous phenoxybenzamine for alpha-blockade before undergoing urgent coronary angiography. This revealed minor coronary artery disease. Left ventriculogram demonstrated akinesis in the apex with hypercontra...

Pheochromocytomas are rare neuro-endocrine tumors arising from chromaffin cells of the sympathetic nervous system.Pheochromocytomacan have diverse clinical presentations, which makes the diagnosis often difficult. We present a case of adrenalpheochromocytoma presenting as acute ST elevation myocardial infarction (STEMI). Catecholamine surge in patients with pheochromocytoma can cause myocardial...

We report a case with pheochromocytoma presenting as recurrent syncope due to hypotension. A 71-year-old man was admitted because of recurrent syncope and paroxysmal hypotension. He was diagnosed as having pheochromocytoma. In spite of a large volume of infusion and insulin therapy, syncope and paroxysmal hypotension continued. We speculated that hypotension was mainly due to vasodilatation cau...

Neurofibromatosis 1 is a rare inherited autosomal dominant syndrome. It comprises 90 % of neurofibromatosis cases. These patients may develop various types of tumours in early age, especially multiple neurofibromas with a high risk of developing malignant peripheral nerve sheath tumours. Other tumours can also develop like pheochromocytoma, optic nerve and brain stem gliomas, carcinoids and rar...

Pheochromocytoma is one of recurrent tumors in patients with von Hippel-Lindau (VHL) disease. For bilateral adrenal glands, unilateral adrenalectomy the treatment choice; however, for a single gland, hemiadrenalectomy or tumorectomy can be performed instead to preserve function. Currently, recommended even if pheochromocytomas occur residual tissue. Consequently, insufficiency cannot avoided th...

Pheochromocytoma is a rare neuroendocrine tumor presenting with classical triad of symptoms. In 10% the cases presentation can be atypical, and diagnosis often missed for several years. Most common neurological manifestations are haemorrhage, seizures, etc., but pheochromocytoma crisis as delirium has been infrequently reported. We present case middle-aged female who presented hypertensive emer...