Reaction of sodium salt of allyl alcohol with 2-chloro-5-phenyl- l,3,4-thiadiazole gave 2-allyloxy-5-phenyl-1,3,4-thiadiazole 2. Compounds 4a and 4b could be obtained through the reaction of nitrone 3 with 2. Reaction of compound 2 with nitrone 5 afforded the final compound 6. Antifungal activity of all compounds was less than ketoconazole

       Keeping in view the promising potential of carbonic anhydrase inhibitor based antimicrobials and enhancement of carbonic anhydrase inhibitory activity by metal complexes of sulfonamides, with an aim to develop better antimicrobial agents we have attempted investigation of antimicrobial activity of metal complexes of 4-(2'-hydroxy phenyl imino) phenyl sulphonamide. Sulfanilamide was taken...

Some reactive dyes (6a-6l) having Quinazolin-4(3H)-one system have been synthesized by coupling of diazotized 3-(4-(5-(4-aminophenyl)-1,3,4-oxadiazol-2-yl) phenyl)-4-oxo-2-phenyl-3,4-dihydroquinazoline-6-sulphonic acid with cyanurated components such as H-acid, J-acid, N-methyl Gamma acid, Peri Sulpho Tobias Koch Bronners Chicago K-acid, N-Phenyl J-acid and M-acid. The were characterized nitrog...

New 6-CF3-1H-pyrazolo[3,4-b]quinolines with a methyl and/or phenyl group attached to the pyrazole core (Molx (x = 1, 2, 3, 4)) were synthesized and characterized in terms of their optoelectronic applications: photovoltaic electroluminescence. The fluorescence emissions investigated phenyl-decorated pyrazoloquinolines is caused by photoinduced charge transfer p process occurring between substitu...

Diabetes mellitus is a widespread disease in the world, despite advances understanding molecular mechanisms of development multifactorial processes associated with this nosology. The review material devoted to modern ideas about immunogenetic causes diabetes, changes metabolism violation carbohydrate metabolism, types and principles laboratory diagnostics accordance WHO criteria. Information on...