Some matrix chemicals used in MALDI mass spectrometry are not sufficiently vacuum-stable and therefore suitable for extended imaging experiments. Caging the matrices by covalent attachment of a photocleavable group renders them vacuum-stable, as reported Qiuqin Zhou et al. their Research Article (e202217047). The caged is eventually uncaged situ UV laser ion source. Thereby, original liberated,...

OBJECTIVE Given the limited effectiveness of pharmacological treatments, non-pharmacological interventions to treat Alzheimer's disease (AD) have gained attention in recent years. The aim of the present study is to investigate the effects of anodal tDCS (AtDCS) combined with memory training on face-name associations in an AD patient sample. METHODS Thirty six AD patients were randomly assigne...

OBJECTIVE To analyze the interventions performed by health professionals with a view to managing chemotherapy-induced febrile neutropenia. METHOD Integrative literature review, the sample of 12 primary articles was selected from the following databases: LILACS, SciELO, BVS, PubMed, CINAHL and Web of Science. RESULTS There was a prevalence of studies, realized by doctors, focused on pharmaco...

We report on the electrochemical detection of anti-cancer drugs in human serum with sensitivity values in the range of 8-925 nA/μM. Multi-walled carbon nanotubes were functionalized with three different cytochrome P450 isoforms (CYP1A2, CYP2B6, and CYP3A4). A model used to effectively describe the cytochrome P450 deposition onto carbon nanotubes was confirmed by Monte Carlo simulations. Voltamm...

the effect of non – pharmacologic pain management methods for venipuncture pain in school aged children in the center for thalassemia in the city of kerman     bageriyan s [1] , borhani f [2] *, abaszadeh a [3]     received: 12 sep, 2012 accepted: 20 nov, 2012   abstract   background & aims : establishing intravenous line (iv catheter) is one of the most common invasive procedures that cause pa...