The effects of magnesium stearate (MgSt) and shear stress on flow properties and hydrophobicity are not well known. Blends with different concentrations of magnesium stearate and varying amounts of shear were tested using three different procedures: the FT4 Rheometer test, a tap density analyzer, and the Washburn method, to better understand the relation of lubricant concentration, amount of sh...

The molecular structure of a candidate pharmaceutical drug compound is routinely modified during lead optimisation. While the difference in pharmacological effect may be subtle, on solid-state landscape...

The indiscriminate and injudicious use of second generation fluoroquinolones viz., enrofloxacin produced anemia, leucopenia, hypoglycaemia, hypoproteinemia, increased enzymatic activity and hepatotoxic and nephrotoxic effects in broiler chickens. Exposure to heavy metals results in congestion and hemorrhages in the lungs, tubular degeneration in kidneys and occasional hemorrhages in the brain. ...

This study provides an overview of policy measures targeting pharmaceutical expenditure in Europe and analyses their impact on originator pharmaceutical prices. Panel data methods are used to examine the market of ACE Inhibitors in six European countries (Denmark, France, Germany, Netherlands, Sweden, United Kingdom) over period 1991-2006. We find that although some measures are effective in re...

What does the demand for pharmaceuticals look like? How effectively does a price cut control pharmaceutical expenditure? To shed light on these questions, I estimate the demand for antihypertensive drugs in Korea (2003-2007) using NLM. The estimation results are following. 1) Physicians are not sensitive to price differences and the price elasticity of the original drugs is further reduced afte...

Pharmaceutical industry is currently undergoing a transient phase with new orientation. Loss of financial resources, presence of new therapeutic agents and increasing cost of research and development have called for a full.scale restructuring within the pharmaceutical industry to retain even the most basic competitiveness. The development of new technologies has been as one way out of the dile...

funding combination is the most important issue for the companies while they know the amount of required capital. companies should be careful regarding the appliance of financial providing methods compatible with the investment strategy of company and profitability. this study seeks to examine the relationship between the capital structure and the profitability of pharmaceutical companies in ir...

pharmaceutical products prepared in pharmacies have the potential of contamination with different microorganisms. this is in part due to the unhygienic environment and also lack of a suitable preservative system. in this study, microbial quality of eucerin-urea ointments prepared at different pharmacies in tehran, at the point of sale and also after two weeks storage at room temperature was exa...