Surfaces obtained by modifying poly(N,N'-dimethylaminoethyl methacrylate) (PDMAEMA) on rough silicon substrates are highly hydrophilic at low pH and highly hydrophobic at high pH; such surfaces effectively supplement the research on the wettability of solid surfaces based on the pH-responsive polymers.

We establish a novel mathematical model to describe and analyze pH levels in the vicinity of poly(N-vinylcaprolactam-co-acetoacetoxyethyl methacrylate-co-N-vinylimidazole) (VCL/AAEM/VIm) microgel-functionalized polymers during biodegradation. Biodegradable polymers, especially aliphatic polyesters (polylactide/polyglycolide/polycaprolactone homo- and copolymers), have a large range of medical a...

A variable optical attenuator (VOA) based on polymer stabilized twisted nematic (PSTN) liquid crystal (LC) is demonstrated. Comparing with the normal twisted nematic LC-based VOA, PSTN exhibits a much faster response time. Moreover, the polymer networks effectively eliminate the backflow effect which exists in the normal TNLC cell. The attenuation mechanism of the PSTN LC was studied. Both pola...

the aim of this study was to investigate the rheological behavior and mucoadhesive nature of saliva substitutes, by incorporating various mucoadhesive polymers into an artificial saliva pump spray formulation. for this purpose various mucoadhesive polymers including cellulosic polymers in the range of 0.1-1.0% and carbomers such as c974p, c971, c934p and c971 in the range of 0.01-0.1% were adde...

Nanoparticles may limit off-tumor/on-target ubiquitous activation of signaling by protein-based drugs. However, many challenges still exist in the design a nanoparticle for protein delivery. In this study, conditions to establish vaterite nanoparticles as pH-sensitive drug delivery system (DDS) encapsulated drugs are comprehensively evaluated. Low coprecipitation pH and prevents denaturation yi...

Structural changes of pyrene-labeled and unlabeled poly(maleic acid/octyl vinyl ether) (PMAOVE) and poly(maleic acid/methyl vinyl ether) (PMAMVE) with changes in pH have been investigated in this study. The changes in the photophysical properties of pyrene are interpreted to investigate uncoiling or swelling of the polymeric chains with pH. The vibrational fine structure of the pyrene fluoresce...

A novel tellurium-containing polymer micelle system is reported to be responsive to 100 μM H2O2 and can undergo a series of morphological changes. The polymer micelles also respond to 2 Gy gamma radiation, which is the exact dosage a patient receives per day for clinical radiation therapy.

Water-soluble metal-binding polymers in combination with ultrafiltration are shown to be an effective method for selectively removing dilute actinide ions from acidic solutions of high ionic strength, The actinirte-binding properties of commercially available water-soluble polymers and several polymers which have been repotted in the literature were evrduated, The functional groups incorporated...

rug delivery to the colon is beneficial not only for the oral delivery of proteins and peptide drugs (degraded by digestive enzymes of stomach and small intestine) but also for the delivery of low molecular weight compounds used to treat diseases associated with the colon or large intestine such as ulcerative colitis, diarrhea, and colon cancer. In addition, the colon has a long retention time ...