Objectives: To compare the efficacy of Ketorolac and Pethidine for postoperative pain relief in first 24 hours after tonsillectomy. Patients & methods: This comparative study was conducted at Anaesthesia Department PGMI Hayatabad Medical Complex, Peshawar between December, 2004 to May 2005. One hundred patients age 5-12 years under going tonsillectomy were divided into group A and B randomly, w...

This study investigated efficacy and side effects of Morphine suppository for pain management after the first elective caesarean delivery in comparison to Diclofenac suppository. One hundred women aged 18-40 with term pregnancies undergoing elective caesarean section for the first time participated in this prospective project. Exclusion criteria included drug sensitivity, fetal malformations or...

The ventilatory effects of three doses of meptazinol (20 mg, 30 mg and 48 mg) were studied in anaesthetized patients and compared with those of pethidine 20 mg. Minute volume, tidal volume, ventilatory frequency, inspiratory and expiratory times were measured and mean inspiratory flow rates calculated. Each patient received a first dose of drug which was followed after 5 min by a second identic...

The effects of various cardiovascular drugs (prostaglandin E2 (PGE2), propranolol and nitroglycerine) and anaesthetic regimens (halothane, pethidine and pentobarbitone), upon the outcome of coronary artery ligation in acutely prepared rats were determined. Effects upon arrhythmias, blood pressure, heart rate, mortality, ECG and the size of the occluded zone were determined for each drug in the ...

We have investigated in mice the effects of several drugs which may be administered as part of an anaesthetic technique on the convulsive threshold to laudanosine and to strychnine, which is reported to have a similar mechanism of action. I.v. administered propofol, thiopentone and midazolam increased the dose of convulsant necessary to produce seizure when administered 2 min before the convuls...