Dietary exposure of Inuit people to a mixture of pesticides and polychlorinated biphenyls, or persistent organic pollutants (POPs), during pregnancy is a public health concern. We examined the consequences of administering the mixture of 28 POPs found in the Inuit diet (at doses representing 10-1000 times dietary levels) by gavage to pregnant Sprague-Dawley rats either during gestation days 0-1...

The Stockholm Convention (SC) on persistent organic pollutants (POPs) has highlighted the global risk(s) posed by organic contaminants that are persistent, bioaccumulate, are prone to long-range transport, and have the potential to cause adverse effects in humans and wildlife (1). As a result of the SC, monitoring programs are underway to record concentrations of POPs across the globe over time...

BACKGROUND Research suggests that estrogenic endocrine-disrupting chemicals interfere with lactation. OBJECTIVES (1) to determine if estrogenic persistent organic pollutants (POPs) are associated with shortened lactation duration; (2) to determine whether previous breastfeeding history biases associations. METHODS AND RESULTS We measured selected organochlorines and polychlorinated biphenyl...

The natural reservoir for influenza A virus (IAV) is wild aquatic birds, where the virus transmits usuallywith low-pathogenicity to the hosts. However, these viruses can spillover into other animals, includingmarine mammals and humans, with devastating consequences: causing outbreaks and in some casesmass mortalities. Marine mammals, at the top of their food chains, are highly conta...

Persistent organic pollutants (POPs) have been of environmental and health concern for more than half a century and have their own intergovernmental regulation through the Stockholm Convention, from 2001. One major concern is the nursing child's exposure to POPs, a concern that has led to a very large number of scientific studies on POPs in mothers' milk. The present review is a report on the a...

The presence of toxic substances such as persistent organic pollutants (POPs) in the environment, and in organisms including humans, is a serious public health and environmental problem, even at low levels and poses a challenging scientific problem. The Stockholm Convention on POPs (SC) entered into force in 2004 and is a large international effort under the United Nations Environment Programme...

BACKGROUND Persistent organic pollutants (POPs), which are endocrine disruptors that accumulate in adipose tissue, can increase the risk of periodontal disease through the disturbance of the immune system. OBJECTIVE We examined associations of background exposure to POPs with periodontal disease in the general population. DESIGN Cross-sectional associations of concentrations of serum POPs w...

BACKGROUND Persistent organic pollutants (POPs) are hazardous chemicals omnipresent in our food chain, which have been internationally regulated to ensure public health. Initially described for their potency to affect reproduction and promote cancer, recent studies have highlighted an unexpected implication of POPs in the development of metabolic diseases like type 2 diabetes and obesity. Based...