peroxisome proliferator activated receptor γ

mehrnoosh shanaki bavarsad department of biochemistry, school of medicine, tehran university of medical sciences, tehran, iran taghi golmohammadi department of biochemistry, school of medicine, tehran university of medical sciences, tehran, iran arash hossein-nezhad department of medicine, section of endocrinology, nutrition, and diabetes, vitamin d, skin and bone research laboratory, boston university medical center, boston, massachusetts, united states of america reza meshkani department of biochemistry, school of medicine, tehran university of medical sciences, tehran, iran maani beigy students&rsquo; scientific research center (ssrc) ,tehran university of medical sciences, tehran, iran mahmoud shirzad cardiovascular surgery department, tehran heart center ,tehran university of medical sciences, tehran, iran

background: coronary artery disease (cad) is the major cause of mortality and morbidity worldwide. the aim of this study was to explore the effect of resveratrol (res) on canonical β-catenin/wnt and forkhead box o (foxo) pathways in cad patients.method: we performed this study on 10 metabolic syndrome patients with three-vessel cad and 10 sex-aged matched healthy subjects. the effects of res on...

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Acetylenic acid analogues from the edible mushroom Chanterelle (Cantharellus cibarius) and their effects on the gene expression of peroxisome proliferator-activated receptor-gamma target genes.

Journal: :Bioorganic & medicinal chemistry letters 2012

Seong Su Hong Ji Hae Lee Wonsik Jeong Nahyun Kim Hui Zi Jin Bang Yeon Hwang Hak-Ju Lee Sung-Joon Lee Dae Sik Jang Dongho Lee

A new acetylenic acid, (10E,14Z)-9-oxooctadeca-10,14-dien-12-ynoic acid (1), was isolated from the edible mushroom Chanterelle (Cantharellus cibarius), together with a known acetylenic acid, (10E,14Z)-9-hydroxyoctadeca-10,14-dien-12-ynoic acid (2) and their structures were determined through analysis of NMR and mass data. The new acetylenic acid (1) specifically activated peroxisome proliferato...

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Peroxisome proliferator-activated receptors: roles in tumorigenesis and chemoprevention in human cancer.

Journal: :Current opinion in oncology 2001

B H Park B Breyer T C He

Peroxisome proliferator-activated receptors are nuclear receptors that were isolated for their ability to modulate lipid metabolism. Similar to other members of the nuclear receptor family, peroxisome proliferator-activated receptors bind ligand as heterodimers and exert their effects via transcriptional regulation through their DNA binding domains. During the past decade, it has become clear t...

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