BACKGROUND Peripheral nerve injury causes physiological changes in primary afferent neurons. Neuropathic pain associated with peripheral nerve injuries may reflect changes in the excitability of the nervous system, including the spinothalamic tract. Current alternative medical research indicates that acupuncture stimulation has analgesic effects in various pain symptoms. However, activation cha...

To evaluate the effects of local administration of the fetal brain extract (FBE) on the crushed peripheral nerve, 15 male Wistar rats were used. The right sciatic nerve of 10 rats was locally underwent the tense compression for 30 seconds and then randomly divided into experimental and control (sham) groups. The remained rats were considered as intact animals. Treatment was commenced weekly, by...

objectives to compare an out-of-plane interscalene catheter technique to the in-plane technique in a randomized clinical trial. patients and methods eighty-four patients undergoing open shoulder surgery were randomized to either the in-plane or out-of-plane ultrasound-guided continuous interscalene technique. the primary outcome was vas pain rating at 24 hours. secondary outcomes included pain ...

Two to twelve weeks after crushing a muscle nerve, still before the damaged afferents reinnervate the muscle receptors, conditioning stimulation of group I fibers from flexor muscles depolarizes the damaged afferents [M. Enriquez, I. Jimenez, P. Rudomin, Changes in PAD patterns of group I muscle afferents after a peripheral nerve crush. Exp. Brain Res., 107 (1996), 405-420]. It is not known, ho...

The aim of this retrospective study is to evaluate the role of the implanted peripheral nerve stimulator in patients with pain in a peripheral nerve distribution. The current study is the largest in the literature that examines the role of the implantable peripheral nerve stimulator in the chronic pain patient. Our patient sample included 38 patients (with 41 nerve stimulators), consisting of 1...

Deafferentation induced by local anesthesia causes a larger perceived area than the real of mouth, which, in perspective body representation, belongs to implicit representation. In this study, we applied repetitive peripheral magnetic stimulation (rPMS) on motor branch radial nerve participants’ non-dominant-side forearm induce extension movements wrist and fingers. This intervention was suppos...

Stimulation of peripheral cranial nerves has been shown to exert anticonvulsant effects in animal models as well as in human patients. Specifically, stimulation of both the trigeminal and vagus nerves has been shown in multiple clinical trials to be anticonvulsant, and stimulation of these nerves at therapeutic levels does not cause pain or negatively affect brain function. However, the neurona...

By measuring blood flow in the ascending aorta with an electromagnetic flowmeter, continuous observations of cardiac output were performed in the dog during various cardiovascular reflexes. Attempts were made to analyze how changes in cardiac output and peripheral resistance contributed to each reflex. The depressor reflex to sinus nerve stimulation was attributable to three separate processes ...