The aim of the present study was to evaluate the effect of gamma irradiation on the hereditary structures of peripheral blood lymphocytes and to quantify this in a dose-effect study. We used adult male rabbits subjected to total gamma irradiation at a dose range of 0.5 − 3.0 Gy. Twenty-four (24) hours later, we began the process of culturing and determination of chromosome aberration frequency ...

Introduction: Dental Cone beam CT (CBCT) is an imaging modality which has emerged as a 3D imaging modality of choice for osseous structures in the maxillofacial region. With increased usage of CBCT imaging for diagnosis and treatment planning, it is imperative that stringent dose assessments must be performed for dose estimation to safeguard both the patients and operating staf...

A Phase I dose escalation and pharmacokinetic study of the alkylating cytotoxic agent treosulfan was conducted to evaluate the maximum tolerated dose and the dose-limiting toxicities in patients with advanced malignancies rescued by autologous peripheral blood stem cell transplantation. Twenty-two patients (15 ovarian and 7 other carcinomas/lymphomas) with a median age of 48 years were treated ...

Background: Intraoperative radiation therapy (IORT) technique is used to treat a surgically exposed tumor or tumor bed in the treatment of locally advanced intraabdominal, retroperitoneal, pelvic, thoracic, breast and soft tissue tumors. One way to perform IORT is to use an existing linac and modify the treatment head using an applicator system. In this study the objectives were to design, and ...

background: in vivo dosimetry is a method for estimation of overall error in the delivered dose to the patients at the end of radiotherapy process. in this research, two methods for target dose calculation were evaluated on midline and central axis of photon beams in in vivo dosimetry of thorax fields. materials and methods: entrance and exit doses for anterior and lateral fields of thorax were...

the frequency of chromosomal aberrations was studied in the peripheral blood lymphocytes of 65 radiology technologists crt) working at hospitals chronically exposed to x-rays. although film dosimetry did not show the maximal annual permitted dose in any of the examined subjects, cytogenetic analysis detected fairly high levels of chromosomal aberrations in r t compared to unexposed controls. th...

Aim: Interventional radiology procedures using ionizing radiation were frequent and become more and more complex. While determinants of radiation exposure during coronary angioplasty have been examined intensively during the last decade, available data regarding peripheral interventional procedures and especially the influence of pre-interventional diagnostic procedures on radiation exposure ar...

BACKGROUND The decrease in peripheral blood lymphocytes induced by radiation lessens the antitumour effect of the immune response, which might cause immunosuppression. We aimed to investigate the correlation between the decrease in peripheral blood lymphocytes during radiotherapy (RT) and the spleen irradiation dose in patients with hepatocellular carcinoma (HCC). METHODS The subjects were 59...

introduction: esophageal cancer is one of the most frequently occurring cancers in iran and having a  high  incidence  rate  among  other  countries.  radiotherapy  is  one  of  the  three  methods  (surgery,  radiotherapy and chemotherapy) for radical or palliative treatment of esophageal cancer. in this method  of treatment, the organs such as heart and spinal cord are regarded as organs at r...