We describe a 37-year-old man with a 4-month history of episodic muscular weakness, involving mainly lower-limbs. Hypokalemia was documented in one episode and managed with intravenous potassium chloride. Hyperthyroidism was diagnosed 4 months after onset of attacks because of mild symptoms. The patient was subsequently diagnosed as having thyrotoxic periodic paralysis associated with Graves' d...

... 

CONTEXT The aim of this article was to review the clinical presentation, pathogenesis, and management of thyrotoxic periodic paralysis (TPP). EVIDENCE ACQUISITION A MEDLINE search was conducted for articles published during the last 40 yr based on the key words thyrotoxic periodic paralysis and hypokalemic periodic paralysis. A total of 281 primary articles and 168 references of the retrieved...

BACKGROUND The periodic health evaluation (PHE) has been a fundamental part of medical practice for decades despite a lack of consensus on its value. PURPOSE To synthesize the evidence on benefits and harms of the PHE. DATA SOURCES Electronic searches of such databases as MEDLINE and the Cochrane Library, review of reference lists, and hand- searching of journals through September 2006. S...

In this paper, we consider inventory models for periodic-review systems with replenishment cycles, which consist of a number of periods. By replenishment cycles, we mean that an order is always placed at the beginning of a cycle. We use dynamic programming to formulate both the backorder and lost-sales models, and propose to charge the holding and shortage costs based on the ending inventory of...

We consider the periodic review inventory control problem in which the purchasing cost of the product changes, in a Markovian fashion, from one period to the next. After establishing (with and without the non-speculation assumption) that an order upto policy is optimal, we develop an efficient recursive solution procedure to compute the optimal levels. In addition, we propose a measure for the ...

The polar regions of Mars preserve, in both their layering and their topography, a record of recent climate changes. Because of the coincidence of the growth of the northern seasonal cap with global dust storms, dust may be currently accumulating on the northern cap, but conditions at the poles will alternate with the precessional cycle. Deposition is also modulated by changes in eccentricity a...