A catalytic spectrophotometric method for determination of ultra-trace quantities of manganese(II) id described. The method is based on the catalytic effect of manganese(II) on the oxidation reaction of ferroin by potassium periodate in acidic media. The reaction is monitored spectrophotometrically at 510 nm by a slope method and Mn(II) is determinable in the range of 1-1000ngmL-1</sup...

The effect of adenosine dialdehyde (AD) on in situ tumor growth and host survival was evaluated in the C1300 murine neuroblastoma tumor model prepared by implantation of murine neuroblastoma cells into A/J mice. AD was administered s.c. by one of the following treatment regimens: regimen A, single daily dose for 5 days; regimen B, minipump infusion for 7 days; regimen C, minipump infusion for 1...

寺 田喜久雄,西 村 かず よ,木 羽敏泰:金 沢大学理学部化学教室,金 沢市丸 の内1-1〒920 A simple and effective method for determining 106Ru in sea water is presented. After the sea water is heated with oxidants (potassium peroxodisulfate and potassium periodate) in potassium hy droxide solution, ruthenium tetraoxide is extracted into carbon tetrachloride from the aqueous solution adjusted to pH 4-6, and then back-extracted with a ...

Protein isoaspartyl methyltransferase is implicated in the repair of age-damaged proteins containing atypical, isoaspartyl linkages. To test the prediction that isoaspartyl proteins would accumulate during methyltransferase inhibition, rat PC12 cells were treated with the indirect methylation inhibitor, adenosine dialdehyde. We observed a marked, dose- and time-dependent, reversible accumulatio...