The purpose of this study was to evaluate the ability of mineral trioxide aggregate (MTA) and amalgam to seal furcal perforations in extracted human molars using an anaerobic bacterial leakage model. Furcal perforations were made in 39 maxillary and mandibular human molars with a high-speed bur. These were randomly divided into two experimental groups of 18, with the remaining three teeth used ...

Listeria monocytogenes (Lm) evade microbicidal defences inside macrophages by secreting a pore-forming cytolysin listeriolysin O (LLO), which allows Lm to escape vacuoles. LLO also inhibits Lm vacuole fusion with lysosomes, which indicates LLO alters vacuole chemistry prior to release of Lm into cytoplasm. Using fluorescent probes to measure membrane permeability, calcium and pH, we identified ...

PURPOSE The aim of the present study was to evaluate the sinus membrane perforations that occurred during a sinus lift procedure using the ultrasound technique, and to evaluate the bone gain obtained. MATERIALS AND METHODS In 21 patients, 26 sinus lifts were performed using ultrasound and filled with bone graft material. The bone height and the bone gain obtained were observed in postoperativ...

We report perforations of a pregnant uterus during laparoscopy for suspected internal herniation after gastric bypass at 24 weeks of gestation. Abdominal access and gas insufflation were achieved by the use of a 12 mm optic trocar. An additional 5 mm trocar was positioned. The perforations were handled by suturing following laparotomy and mobilisation of the high located uterus. The uterine fun...

The perforations of the tympanic membrane maybe of traumatic origin or due to chronic suppurative otitis media. If the perforations fail to heal conservatively, they require surgical closure. Autologous graft materials have stood the test of time in repairing tympanic membrane perforations. In our tertiary care institution we conducted a prospective randomized control trial on 50 subjects to ev...

Gastrointestinal perforations, which need to be managed quickly, are associated with high morbidity and mortality. Treatments used to close these perforations range from surgery to endoscopic therapy. Nowadays, with the development of new devices and techniques, endoscopic therapy is becoming more popular. However, there are different indications and clinical efficacies between different method...

A technique utilizing modified Gates Glidden burs and ultrasonics has recently been advocated to remove fractured instruments from root canals. Varying extents of tooth structure are removed during this procedure, potentially leading to complications. This study evaluated the in vitro and in vivo complications associated with fractured file removal. Fractured instrument fragments were removed f...

The present paper reports the laminar fluid flow and heat transfer of a heated array of circular-perforated and solid fins mounted over a flat surface using the finite-volume method. One to four circular cross-sectional perforations are made along the length of the fins. The SIMPLE algorithm is used for pressure-velocity coupling and the second order upwind technique is employed to discreti...

PURPOSE To investigate the integration of subretinal implants containing full-depth perforations of various widths with rat and pig retina across weeks of implantation. METHODS In transgenic P23H rhodopsin line 1 (TgP23H-1) rats and wild-type (WT) pigs, we examined four subretinal implant designs: solid inactive polymer arrays (IPA), IPAs with 5- or 10-μm wide perforations, and active bipolar...

Perforations of peptic ulcers account for between 5 % and 8% of abdominal conditions submitted to urgent laparotomy. The general practitioner may see less than one case a year even though in an average-sized practice he has many patients with peptic ulcers. This relative rarity of the complication of perforation in the experience of the individual practitioner does not often lead to difficulty ...