OBJECTIVES This study was designed to compare the long-term consequences of percutaneous transluminal coronary angioplasty (PTCA) and continued medical treatment. BACKGROUND The long-term effects of percutaneous coronary intervention need evaluating, especially in comparison with an alternative policy of continued medical treatment. METHODS The Second Randomized Intervention Treatment of An...

In this issue of Circulation, Detre et all review the incidence and outcome of periprocedural coronary artery occlusion following percutaneous transluminal coronary angioplasty (PTCA) in the second phase of the National Heart, Lung, and Blood Institute's (NHLBI) PTCA Registry. This registry examined the results in 1,801 patients managed during 1985-1986 with an initial PTCA not in the setting o...

The advent of stents has profoundly changed percutaneous transluminal coronary angioplasty (PTCA), peripheral transluminal artery angioplasty (PTA), and treatment strategies of numerous other problems. Similar developments can be observed for stent applications in peripheral vascular lesions, cerebro-vascular disease, and many other fields. With the advent of covered stent-grafts, aneurysm surg...

Percutaneous Transluminal Coronary Angioplasty To the Editor: Manegold et al1 compared the incidence of prior cytomegalovirus (CMV) infection and the risk of restenosis after percutaneous transluminal coronary angioplasty (PTCA) in 92 consecutive patients. A total of 65% of these patients were positive for IgG CMV antibodies. At 6 months, angiographic restenosis was similar in CMV-positive and ...

OBJECTIVE To determine whether inhibition of angiotensin converting enzyme (ACE) can prevent angiotensin II production in the coronary circulation induced by percutaneous transluminal coronary angioplasty (PTCA) in patients with myocardial ischaemia. DESIGN, PATIENTS 41 patients who underwent elective PTCA and six control subjects who received diagnostic coronary angiography were studied. Pat...

Background—In the era of primary percutaneous transluminal coronary angioplasty (PTCA), it is important to judge whether myocardium within acute ischemic injury is viable. This study sought to investigate parameters derived from the coronary blood flow velocity spectrum immediately after primary PTCA in patients with acute myocardial infarction and to elucidate the clinical value of coronary bl...

In this issue of Circulation, Detre et all review the incidence and outcome of periprocedural coronary artery occlusion following percutaneous transluminal coronary angioplasty (PTCA) in the second phase of the National Heart, Lung, and Blood Institute's (NHLBI) PTCA Registry. This registry examined the results in 1,801 patients managed during 1985-1986 with an initial PTCA not in the setting o...

BACKGROUND Risks of coronary artery bypass graft surgery (CABG) or percutaneous transluminal coronary angioplasty (PTCA) may be different in the presence of peripheral vascular disease (PVD). METHODS AND RESULTS We analyzed outcomes of 550 patients with PVD enrolled in the Bypass Angioplasty Revascularization Investigation randomized trial and registry. Compared with 1770 patients without PVD...

Periprocedural thrombus formation is not only responsible for one of the most serious complications of percutaneous transluminal coronary angioplasty, acute thrombotic occlusion of the coronary artery, but has also been postulated as the initial trigger of pathophysiological mechanisms leading to restenosis. The latter hypothesis is based on experimental findings showing that thrombin activatio...

BACKGROUND Restenosis after initial, successful percutaneous transluminal coronary angioplasty (PTCA) is due to fibrocellular proliferation. METHODS AND RESULTS The present study focused on the nature of fibrocellular tissue in humans by use of immunocytochemical techniques. Four hearts (five coronary arteries) were investigated; time lapse between PTCA and death varied between 20 days (two a...